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1163. Computer-Aided Diagnosis for Leaving Colorectal Polyps In Situ : A Systematic Review and Meta-analysis.
作者: Cesare Hassan.;Masashi Misawa.;Tommy Rizkala.;Yuichi Mori.;Shahnaz Sultan.;Antonio Facciorusso.;Giulio Antonelli.;Marco Spadaccini.;Britt B S L Houwen.;Emanuele Rondonotti.;Harsh Patel.;Kareem Khalaf.;James Weiquan Li.;Gloria M Fernandez.;Pradeep Bhandari.;Evelien Dekker.;Seth Gross.;Tyler Berzin.;Per Olav Vandvik.;Loredana Correale.;Shin-Ei Kudo.;Prateek Sharma.;Douglas K Rex.;Alessandro Repici.;Farid Foroutan.; .
来源: Ann Intern Med. 2024年177卷7期919-928页
Computer-aided diagnosis (CADx) allows prediction of polyp histology during colonoscopy, which may reduce unnecessary removal of nonneoplastic polyps. However, the potential benefits and harms of CADx are still unclear.
1164. Sensitivity and Specificity of Using GPT-3.5 Turbo Models for Title and Abstract Screening in Systematic Reviews and Meta-analyses.
作者: Viet-Thi Tran.;Gerald Gartlehner.;Sally Yaacoub.;Isabelle Boutron.;Lukas Schwingshackl.;Julia Stadelmaier.;Isolde Sommer.;Farzaneh Alebouyeh.;Sivem Afach.;Joerg Meerpohl.;Philippe Ravaud.
来源: Ann Intern Med. 2024年177卷6期791-799页
Systematic reviews are performed manually despite the exponential growth of scientific literature.
1166. Artificial Intelligence for Real-Time Prediction of the Histology of Colorectal Polyps by General Endoscopists.
作者: Douglas K Rex.;Indira Bhavsar-Burke.;Daniel Buckles.;James Burton.;Amanda Cartee.;Kevin Comar.;Adam Edwards.;Blair Fennimore.;Monika Fischer.;Mark Gerich.;Ashley Gilmore.;Shadi Hamdeh.;Jeffrey Hoffman.;Michael Ibach.;Mollie Jackson.;Toyia James-Stevenson.;Tonya Kaltenbach.;Jeffrey Kaplan.;Saurabh Kapur.;Daniel Kohm.;Michael Kriss.;Shanker Kundumadam.;Kondal R Kyanam Kabir Baig.;Paul Menard-Katcher.;Cary Kraft.;James Langworthy.;Bharat Misra.;Eric Molloy.;Juan Carlos Munoz.;John Norvell.;Thomas Nowak.;Itegbemie Obaitan.;Swati Patel.;Mitesh Patel.;Shajan Peter.;B Marie Reid.;Nicholas Rogers.;Jason Ross.;James Ryan.;Sashidhar Sagi.;Akira Saito.;Salih Samo.;Fayez Sarkis.;Frank I Scott.;Robert Siwiec.;Shelby Sullivan.;Amanda Wieland.;Jianying Zhang.;Alessandro Repici.;Cesare Hassan.;Michael F Byrne.;Amit Rastogi.
来源: Ann Intern Med. 2024年177卷7期911-918页
Real-time prediction of histologic features of small colorectal polyps may prevent resection and/or pathologic evaluation and therefore decrease colonoscopy costs. Previous studies showed that computer-aided diagnosis (CADx) was highly accurate, though it did not outperform expert endoscopists.
1170. A Blueprint for U.S. Health Insurance Reform.
The current U.S. health insurance "system" was not deliberately planned and constructed but has emerged piecemeal over the past half-century through a series of incremental and haphazard reforms. That policy history also reveals a clear but unfulfilled societal commitment to providing access to essential health care regardless of resources. To fulfill this obligation, the solution proposed in this article has 2 key elements: 1) universal coverage that is automatic, free, and basic, and 2) the option to buy supplemental coverage in a well-designed market. Such a system could, if desired, be created without raising taxes and without disrupting or changing the delivery of medical care.
1171. Associations of Testosterone and Related Hormones With All-Cause and Cardiovascular Mortality and Incident Cardiovascular Disease in Men : Individual Participant Data Meta-analyses.
作者: Bu B Yeap.;Ross J Marriott.;Girish Dwivedi.;Robert J Adams.;Leen Antonio.;Christie M Ballantyne.;Douglas C Bauer.;Shalender Bhasin.;Mary L Biggs.;Peggy M Cawthon.;David J Couper.;Adrian S Dobs.;Leon Flicker.;David J Handelsman.;Graeme J Hankey.;Anke Hannemann.;Robin Haring.;Benjumin Hsu.;Sean A Martin.;Alvin M Matsumoto.;Dan Mellström.;Claes Ohlsson.;Terence W O'Neill.;Eric S Orwoll.;Matteo Quartagno.;Molly M Shores.;Antje Steveling.;Åsa Tivesten.;Thomas G Travison.;Dirk Vanderschueren.;Gary A Wittert.;Frederick C W Wu.;Kevin Murray.
来源: Ann Intern Med. 2024年177卷6期768-781页
Whether circulating sex hormones modulate mortality and cardiovascular disease (CVD) risk in aging men is controversial.
1172. Obesity.
作者: Adam H Gilden.;Victoria A Catenacci.;John Michael Taormina.
来源: Ann Intern Med. 2024年177卷5期ITC65-ITC80页
Obesity is a common condition and a major cause of morbidity and mortality. Fortunately, weight loss treatment can reduce obesity-related complications. This review summarizes the evidence-based strategies physicians can employ to identify, prevent, and treat obesity, including best practices to diagnose and counsel patients, to assess and address the burden of weight-related disease including weight stigma, to address secondary causes of weight gain, and to help patients set individualized and realistic weight loss goals and an effective treatment plan. Effective treatments include lifestyle modification and adjunctive therapies such as antiobesity medications and metabolic and bariatric surgery.
1173. Reporting Conflicts of Interest and Funding in Health Care Guidelines: The RIGHT-COI&F Checklist.
作者: Yangqin Xun.;Janne Estill.;Joanne Khabsa.;Ivan D Florez.;Gordon H Guyatt.;Susan L Norris.;Myeong Soo Lee.;Akihiko Ozaki.;Amir Qaseem.;Holger J Schünemann.;Ruitai Shao.;Yaolong Chen.;Elie A Akl.; .
来源: Ann Intern Med. 2024年177卷6期782-790页
Conflicts of interest (COIs) of contributors to a guideline project and the funding of that project can influence the development of the guideline. Comprehensive reporting of information on COIs and funding is essential for the transparency and credibility of guidelines.
1174. Diagnostic Strategy Using Color Doppler Ultrasound of Temporal Arteries in Patients With High Clinical Suspicion of Giant Cell Arteritis : A Prospective Cohort Study.
作者: Guillaume Denis.;Olivier Espitia.;Caroline Allix-Béguec.;Céline Dieval.;Fanny Lorcerie.;Bruno Gombert.;Xavier Pouget-Abadie.;Claire Toquet.;Christian Agard.;Alizée Raimbeau.;Giovanni Gautier.;Jean-Michel Goujon.;Géraldine Durand.;Cécile Thollot-Karolewicz.;Christian Lormeau.;Aurélie Grados.;Anne Grenot-Mercier.;Rony El-Khoury.;Agnès Riche.;Florence Hospital.;Sebastien Visee.;Marie-Luce Auriault.;Cédric Landron.;Mickaël Martin.;Christophe Roncato.
来源: Ann Intern Med. 2024年177卷6期729-737页
Giant cell arteritis (GCA) is the most prevalent systemic vasculitis in people older than 50 years. Any delay in diagnosis impairs patients' quality of life and can lead to permanent damage, particularly vision loss.
1175. In Enterobacterales bacteremia, antipseudomonal β-lactam de-escalation was noninferior to continuation for clinical cure at 3 to 5 d.
López-Cortés LE, Delgado-Valverde M, Moreno-Mellado E, et al; SIMPLIFY study group. Efficacy and safety of a structured de-escalation from antipseudomonal β-lactams in bloodstream infections due to Enterobacterales (SIMPLIFY): an open-label, multicentre, randomised trial. Lancet Infect Dis. 2024;24:375-385. 38215770.
1178. In type 2 diabetes, the effectiveness and side effects of GLP-1 RAs vary.
Yao H, Zhang A, Li D, et al. Comparative effectiveness of GLP-1 receptor agonists on glycaemic control, body weight, and lipid profile for type 2 diabetes: systematic review and network meta-analysis. BMJ. 2024;384:e076410. 38286487.
1179. SCCM issued recommendations for corticosteroid use in acutely ill adults with sepsis, ARDS, or CAP.
Chaudhuri D, Nei AM, Rochwerg B, et al. 2024 focused update: guidelines on use of corticosteroids in sepsis, acute respiratory distress syndrome, and community-acquired pneumonia. Crit Care Med. 2024;52:e219-e233. 38240492.
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