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6343. Discriminative Accuracy of Chronic Obstructive Pulmonary Disease Screening Instruments in 3 Low- and Middle-Income Country Settings.
作者: Trishul Siddharthan.;Suzanne L Pollard.;Shumonta A Quaderi.;Natalie A Rykiel.;Adaeze C Wosu.;Patricia Alupo.;Julie A Barber.;Maria Kathia Cárdenas.;Ram K Chandyo.;Oscar Flores-Flores.;Bruce Kirenga.;J Jaime Miranda.;Sakshi Mohan.;Federico Ricciardi.;Arun K Sharma.;Santa Kumar Das.;Laxman Shrestha.;Marta O Soares.;William Checkley.;John R Hurst.; .
来源: JAMA. 2022年327卷2期151-160页
Most of the global morbidity and mortality in chronic obstructive pulmonary disease (COPD) occurs in low- and middle-income countries (LMICs), with significant economic effects.
6344. Effect of Anticoagulant Therapy for 6 Weeks vs 3 Months on Recurrence and Bleeding Events in Patients Younger Than 21 Years of Age With Provoked Venous Thromboembolism: The Kids-DOTT Randomized Clinical Trial.
作者: Neil A Goldenberg.;John M Kittelson.;Thomas C Abshire.;Marc Bonaca.;James F Casella.;Rita A Dale.;Jonathan L Halperin.;Frances Hamblin.;Craig M Kessler.;Marilyn J Manco-Johnson.;Robert F Sidonio.;Alex C Spyropoulos.;P Gabriel Steg.;Alexander G G Turpie.;Sam Schulman.; .
来源: JAMA. 2022年327卷2期129-137页
Among patients younger than 21 years of age, the optimal duration of anticoagulant therapy for venous thromboembolism is unknown.
6345. Effect of Weekly Subcutaneous Semaglutide vs Daily Liraglutide on Body Weight in Adults With Overweight or Obesity Without Diabetes: The STEP 8 Randomized Clinical Trial.
作者: Domenica M Rubino.;Frank L Greenway.;Usman Khalid.;Patrick M O'Neil.;Julio Rosenstock.;Rasmus Sørrig.;Thomas A Wadden.;Alicja Wizert.;W Timothy Garvey.; .
来源: JAMA. 2022年327卷2期138-150页
Phase 3 trials have not compared semaglutide and liraglutide, glucagon-like peptide-1 analogues available for weight management.
6348. Diagnosis and Treatment of Sexually Transmitted Infections: A Review.
Approximately 1 in 5 adults in the US had a sexually transmitted infection (STI) in 2018. This review provides an update on the epidemiology, diagnosis, and treatment of gonorrhea, chlamydia, syphilis, Mycoplasma genitalium, trichomoniasis, and genital herpes.
6353. Association of a Third Dose of BNT162b2 Vaccine With Incidence of SARS-CoV-2 Infection Among Health Care Workers in Israel.
作者: Avishay Spitzer.;Yoel Angel.;Or Marudi.;David Zeltser.;Esther Saiag.;Hanoch Goldshmidt.;Ilana Goldiner.;Moshe Stark.;Ora Halutz.;Ronni Gamzu.;Marina Slobodkin.;Nadav Amrami.;Eugene Feigin.;Meital Elbaz.;Moran Furman.;Yotam Bronstein.;Amanda Chikly.;Anna Eshkol.;Victoria Furer.;Talia Mayer.;Suzy Meijer.;Ariel Melloul.;Michal Mizrahi.;Michal Yakubovsky.;Dana Rosenberg.;Ari Safir.;Liron Spitzer.;Eyal Taleb.;Ori Elkayam.;Adi Silberman.;Tali Eviatar.;Ofir Elalouf.;Tal Levinson.;Katia Pozyuchenko.;Ayelet Itzhaki-Alfia.;Eli Sprecher.;Ronen Ben-Ami.;Oryan Henig.
来源: JAMA. 2022年327卷4期341-349页
Administration of a BNT162b2 booster dose (Pfizer-BioNTech) to fully vaccinated individuals aged 60 years and older was significantly associated with lower risk of SARS-CoV-2 infection and severe illness. Data are lacking on the effectiveness of booster doses for younger individuals and health care workers.
6355. False-Positive Results in Rapid Antigen Tests for SARS-CoV-2.
作者: Joshua S Gans.;Avi Goldfarb.;Ajay K Agrawal.;Sonia Sennik.;Janice Stein.;Laura Rosella.
来源: JAMA. 2022年327卷5期485-486页
This study examines the incidence of false-positive results in a sample of rapid antigen tests used to serially screen asymptomatic workers throughout Canada.
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