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5665. Population-Based Penetrance of Deleterious Clinical Variants.
作者: Iain S Forrest.;Kumardeep Chaudhary.;Ha My T Vy.;Ben O Petrazzini.;Shantanu Bafna.;Daniel M Jordan.;Ghislain Rocheleau.;Ruth J F Loos.;Girish N Nadkarni.;Judy H Cho.;Ron Do.
来源: JAMA. 2022年327卷4期350-359页
Population-based assessment of disease risk associated with gene variants informs clinical decisions and risk stratification approaches.
5666. Myocarditis Cases Reported After mRNA-Based COVID-19 Vaccination in the US From December 2020 to August 2021.
作者: Matthew E Oster.;David K Shay.;John R Su.;Julianne Gee.;C Buddy Creech.;Karen R Broder.;Kathryn Edwards.;Jonathan H Soslow.;Jeffrey M Dendy.;Elizabeth Schlaudecker.;Sean M Lang.;Elizabeth D Barnett.;Frederick L Ruberg.;Michael J Smith.;M Jay Campbell.;Renato D Lopes.;Laurence S Sperling.;Jane A Baumblatt.;Deborah L Thompson.;Paige L Marquez.;Penelope Strid.;Jared Woo.;River Pugsley.;Sarah Reagan-Steiner.;Frank DeStefano.;Tom T Shimabukuro.
来源: JAMA. 2022年327卷4期331-340页
Vaccination against COVID-19 provides clear public health benefits, but vaccination also carries potential risks. The risks and outcomes of myocarditis after COVID-19 vaccination are unclear.
5669. Screening for Atrial Fibrillation: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force.
作者: Leila C Kahwati.;Gary N Asher.;Zachary O Kadro.;Susan Keen.;Rania Ali.;Emmanuel Coker-Schwimmer.;Daniel E Jonas.
来源: JAMA. 2022年327卷4期368-383页
Atrial fibrillation (AF), the most common arrhythmia, increases the risk of stroke.
5670. Screening for Atrial Fibrillation: US Preventive Services Task Force Recommendation Statement.
作者: .;Karina W Davidson.;Michael J Barry.;Carol M Mangione.;Michael Cabana.;Aaron B Caughey.;Esa M Davis.;Katrina E Donahue.;Chyke A Doubeni.;John W Epling.;Martha Kubik.;Li Li.;Gbenga Ogedegbe.;Lori Pbert.;Michael Silverstein.;James Stevermer.;Chien-Wen Tseng.;John B Wong.
来源: JAMA. 2022年327卷4期360-367页
Atrial fibrillation (AF) is the most common cardiac arrhythmia. The prevalence of AF increases with age, from less than 0.2% in adults younger than 55 years to about 10% in those 85 years or older, with a higher prevalence in men than in women. It is uncertain whether the prevalence of AF differs by race and ethnicity. Atrial fibrillation is a major risk factor for ischemic stroke and is associated with a substantial increase in the risk of stroke. Approximately 20% of patients who have a stroke associated with AF are first diagnosed with AF at the time of the stroke or shortly thereafter.
5673. Clinical Outcomes Among Patients With 1-Year Survival Following Intensive Care Unit Treatment for COVID-19.
作者: Hidde Heesakkers.;Johannes G van der Hoeven.;Stijn Corsten.;Inge Janssen.;Esther Ewalds.;Koen S Simons.;Brigitte Westerhof.;Thijs C D Rettig.;Crétien Jacobs.;Susanne van Santen.;Arjen J C Slooter.;Margaretha C E van der Woude.;Mark van den Boogaard.;Marieke Zegers.
来源: JAMA. 2022年327卷6期559-565页
One-year outcomes in patients who have had COVID-19 and who received treatment in the intensive care unit (ICU) are unknown.
5675. Effect of Noninvasive Respiratory Strategies on Intubation or Mortality Among Patients With Acute Hypoxemic Respiratory Failure and COVID-19: The RECOVERY-RS Randomized Clinical Trial.
作者: Gavin D Perkins.;Chen Ji.;Bronwen A Connolly.;Keith Couper.;Ranjit Lall.;J Kenneth Baillie.;Judy M Bradley.;Paul Dark.;Chirag Dave.;Anthony De Soyza.;Anna V Dennis.;Anne Devrell.;Sara Fairbairn.;Hakim Ghani.;Ellen A Gorman.;Christopher A Green.;Nicholas Hart.;Siew Wan Hee.;Zoe Kimbley.;Shyam Madathil.;Nicola McGowan.;Benjamin Messer.;Jay Naisbitt.;Chloe Norman.;Dhruv Parekh.;Emma M Parkin.;Jaimin Patel.;Scott E Regan.;Clare Ross.;Anthony J Rostron.;Mohammad Saim.;Anita K Simonds.;Emma Skilton.;Nigel Stallard.;Michael Steiner.;Rama Vancheeswaran.;Joyce Yeung.;Daniel F McAuley.; .
来源: JAMA. 2022年327卷6期546-558页
Continuous positive airway pressure (CPAP) and high-flow nasal oxygen (HFNO) have been recommended for acute hypoxemic respiratory failure in patients with COVID-19. Uncertainty exists regarding the effectiveness and safety of these noninvasive respiratory strategies.
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