当前位置: 首页 >> 检索结果
4801. Racial Disparities in Invasive Management for Patients With Acute Myocardial Infarction With Chronic Kidney Disease.
作者: Jennifer A Rymer.;Shuang Li.;Patrick H Pun.;Laine Thomas.;Tracy Y Wang.
来源: Circ Cardiovasc Interv. 2022年15卷1期e011171页
Due to increased risks of contrast nephropathy, chronic kidney disease (CKD) can deter consideration of invasive management for patients with myocardial infarction (MI). Black patients have a higher prevalence of CKD. Whether racial disparities exist in the use of invasive MI management for patients with CKD presenting with MI is unknown.
4802. AtheroSpectrum Reveals Novel Macrophage Foam Cell Gene Signatures Associated With Atherosclerotic Cardiovascular Disease Risk.
作者: Chuan Li.;Lili Qu.;Alyssa J Matz.;Patrick A Murphy.;Yongmei Liu.;Ani W Manichaikul.;Derek Aguiar.;Stephen S Rich.;David M Herrington.;David Vu.;W Craig Johnson.;Jerome I Rotter.;Wendy S Post.;Anthony T Vella.;Annabelle Rodriguez-Oquendo.;Beiyan Zhou.
来源: Circulation. 2022年145卷3期206-218页
Whereas several interventions can effectively lower lipid levels in people at risk for atherosclerotic cardiovascular disease (ASCVD), cardiovascular event risks remain, suggesting an unmet medical need to identify factors contributing to cardiovascular event risk. Monocytes and macrophages play central roles in atherosclerosis, but studies have yet to provide a detailed view of macrophage populations involved in increased ASCVD risk.
4803. DREAM-ICD-II Study.
作者: Christian Steinberg.;Nicolas Dognin.;Amit Sodhi.;Catherine Champagne.;John A Staples.;Jean Champagne.;Zachary W Laksman.;Jean-François Sarrazin.;Matthew T Bennett.;Benoit Plourde.;Marc W Deyell.;Jason G Andrade.;Karine Roy.;John A Yeung-Lai-Wah.;Nathaniel M Hawkins.;Blandine Mondésert.;Louis Blier.;Isabelle Nault.;Gilles O'Hara.;Andrew D Krahn.;François Philippon.;Santabhanu Chakrabarti.
来源: Circulation. 2022年145卷10期742-753页
Regulatory authorities of most industrialized countries recommend 6 months of private driving restriction after implantation of a secondary prevention implantable cardioverter-defibrillator (ICD). These driving restrictions result in significant inconvenience and social implications. This study aimed to assess the incidence rate of appropriate device therapies in contemporary recipients of a secondary prevention ICD.
4804. Factors Associated With Racial and Ethnic Diversity Among Heart Failure Trial Participants: A Systematic Bibliometric Review.
作者: Sunny Wei.;NhatChinh Le.;Jie Wei Zhu.;Khadijah Breathett.;Stephen J Greene.;Mamas A Mamas.;Faiez Zannad.;Harriette G C Van Spall.
来源: Circ Heart Fail. 2022年15卷3期e008685页
Heart failure has a disproportionate burden on patients who are Black, Indigenous, and people of color (BIPOC), but not much is known about representation of these groups in randomized controlled trials (RCTs). We explored temporal trends in and RCT factors associated with the reporting of race and ethnicity data and the enrollment of BIPOC in heart failure RCTs.
4805. Detection of Left Atrial Myopathy Using Artificial Intelligence-Enabled Electrocardiography.
作者: Frederik H Verbrugge.;Yogesh N V Reddy.;Zachi I Attia.;Paul A Friedman.;Peter A Noseworthy.;Francisco Lopez-Jimenez.;Suraj Kapa.;Barry A Borlaug.
来源: Circ Heart Fail. 2022年15卷1期e008176页
Left atrial (LA) myopathy is common in patients with heart failure and preserved ejection fraction and leads to the development of atrial fibrillation (AF). We investigated whether the likelihood of LA remodeling, LA dysfunction, altered hemodynamics, and risk for incident AF could be identified from a single 12-lead ECG using a novel artificial intelligence (AI)-enabled ECG analysis.
4806. Long-Term Outcomes in Adult Patients With Pulmonary Hypertension After Percutaneous Closure of Atrial Septal Defects.
作者: Selai Akseer.;Lusine Abrahamyan.;Douglas S Lee.;Ella Huszti.;Lukas M Meier.;Mark Osten.;Lee Benson.;Eric Horlick.
来源: Circ Cardiovasc Interv. 2022年15卷1期e011110页
Pulmonary hypertension (PH), recently redefined as mean pulmonary arterial pressure >20 mm Hg (PH20), may be observed in patients with atrial septal defects (ASD). We aimed to determine the effect of preprocedural PH20 status on outcomes among patients undergoing ASD closure.
4807. Exercise Training Protects Against Heart Failure Via Expansion of Myeloid-Derived Suppressor Cells Through Regulating IL-10/STAT3/S100A9 Pathway.
作者: Lifeng Feng.;Guangru Li.;Jiale An.;Chang Liu.;Xiaolong Zhu.;Yang Xu.;Yang Gao.;Jing Li.;Jie Liu.;Jie Yan.;Yachen Wang.;Jiling Ren.;Liang Yang.;Zhi Qi.
来源: Circ Heart Fail. 2022年15卷3期e008550页
Exercise training (ET) has a protective effect on the progression of heart failure, however, the specific mechanism has not been fully explored. Myeloid-derived suppressor cells (MDSCs) are a group of myeloid-derived immunosuppressive cells, which showed a protective effect in the progression of heart failure. Thus, we hypothesized that the protective effect of ET on heart failure may be related to the infiltration of MDSCs.
4808. Mechanisms of Sinoatrial Node Dysfunction in Heart Failure With Preserved Ejection Fraction.
作者: Thassio Mesquita.;Rui Zhang.;Jae Hyung Cho.;Rui Zhang.;Yen-Nien Lin.;Lizbeth Sanchez.;Joshua I Goldhaber.;Joseph K Yu.;Jialiu A Liang.;Weixin Liu.;Natalia A Trayanova.;Eugenio Cingolani.
来源: Circulation. 2022年145卷1期45-60页
The ability to increase heart rate during exercise and other stressors is a key homeostatic feature of the sinoatrial node (SAN). When the physiological heart rate response is blunted, chronotropic incompetence limits exercise capacity, a common problem in patients with heart failure with preserved ejection fraction (HFpEF). Despite its clinical relevance, the mechanisms of chronotropic incompetence remain unknown.
4809. Reading Frame Repair of TTN Truncation Variants Restores Titin Quantity and Functions.
作者: Robert Romano.;Shahnaz Ghahremani.;Talia Zimmerman.;Nicholas Legere.;Ketan Thakar.;Feria A Ladha.;Anthony M Pettinato.;J Travis Hinson.
来源: Circulation. 2022年145卷3期194-205页
Titin truncation variants (TTNtvs) are the most common inheritable risk factor for dilated cardiomyopathy (DCM), a disease with high morbidity and mortality. The pathogenicity of TTNtvs has been associated with structural localization as A-band variants overlapping myosin heavy chain-binding domains are more pathogenic than I-band variants by incompletely understood mechanisms. Demonstrating why A-band variants are highly pathogenic for DCM could reveal new insights into DCM pathogenesis, titin (TTN) functions, and therapeutic targets.
4810. Effect of the Glucagon-Like Peptide-1 Receptor Agonists Semaglutide and Liraglutide on Kidney Outcomes in Patients With Type 2 Diabetes: Pooled Analysis of SUSTAIN 6 and LEADER.
作者: Ahmed M Shaman.;Stephen C Bain.;George L Bakris.;John B Buse.;Thomas Idorn.;Kenneth W Mahaffey.;Johannes F E Mann.;Michael A Nauck.;Søren Rasmussen.;Peter Rossing.;Benjamin Wolthers.;Bernard Zinman.;Vlado Perkovic.
来源: Circulation. 2022年145卷8期575-585页
We assessed the effect of once-weekly semaglutide and once-daily liraglutide on kidney outcomes in type 2 diabetes.
4811. Periodic Repolarization Dynamics Identifies ICD Responders in Nonischemic Cardiomyopathy: A DANISH Substudy.
作者: Rune Boas.;Nikolay Sappler.;Lukas von Stülpnagel.;Mathias Klemm.;Ulrik Dixen.;Jens Jakob Thune.;Steen Pehrson.;Lars Køber.;Jens C Nielsen.;Lars Videbæk.;Jens Haarbo.;Eva Korup.;Niels Eske Bruun.;Axel Brandes.;Hans Eiskjær.;Anna M Thøgersen.;Berit T Philbert.;Jesper Hastrup Svendsen.;Jacob Tfelt-Hansen.;Axel Bauer.;Konstantinos D Rizas.
来源: Circulation. 2022年145卷10期754-764页
Identification of patients with nonischemic cardiomyopathy who may benefit from prophylactic implantation of a cardioverter-defibrillator. We hypothesized that periodic repolarization dynamics (PRD), a marker of repolarization instability associated with sympathetic activity, could be used to identify patients who will benefit from prophylactic implantable cardioverter defibrillator (ICD) implantation.
4813. Pulsus Alternans in Cardiogenic Shock Recapitulated in Single Cell Fluorescence Imaging of a Patient's Cardiomyocyte.
作者: Jonathan D Moreno.;Druv Bhagavan.;Allie Li.;Nels C Gerstner.;Evan W Miller.;Nathaniel Huebsch.;Sharon Cresci.;Jonathan R Silva.
来源: Circ Heart Fail. 2022年15卷2期e008855页 4814. 2021 ACC/AHA/SCAI Guideline for Coronary Artery Revascularization: Executive Summary: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.
作者: Jennifer S Lawton.;Jacqueline E Tamis-Holland.;Sripal Bangalore.;Eric R Bates.;Theresa M Beckie.;James M Bischoff.;John A Bittl.;Mauricio G Cohen.;J Michael DiMaio.;Creighton W Don.;Stephen E Fremes.;Mario F Gaudino.;Zachary D Goldberger.;Michael C Grant.;Jang B Jaswal.;Paul A Kurlansky.;Roxana Mehran.;Thomas S Metkus.;Lorraine C Nnacheta.;Sunil V Rao.;Frank W Sellke.;Garima Sharma.;Celina M Yong.;Brittany A Zwischenberger.
来源: Circulation. 2022年145卷3期e4-e17页
The executive summary of the American College of Cardiology/American Heart Association/Society for Cardiovascular Angiography and Interventions coronary artery revascularization guideline provides the top 10 items readers should know about the guideline. In the full guideline, the recommendations replace the 2011 coronary artery bypass graft surgery guideline and the 2011 and 2015 percutaneous coronary intervention guidelines. This summary offers a patient-centric approach to guide clinicians in the treatment of patients with significant coronary artery disease undergoing coronary revascularization, as well as the supporting documentation to encourage their use.
4815. 2021 ACC/AHA/SCAI Guideline for Coronary Artery Revascularization: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.
作者: Jennifer S Lawton.;Jacqueline E Tamis-Holland.;Sripal Bangalore.;Eric R Bates.;Theresa M Beckie.;James M Bischoff.;John A Bittl.;Mauricio G Cohen.;J Michael DiMaio.;Creighton W Don.;Stephen E Fremes.;Mario F Gaudino.;Zachary D Goldberger.;Michael C Grant.;Jang B Jaswal.;Paul A Kurlansky.;Roxana Mehran.;Thomas S Metkus.;Lorraine C Nnacheta.;Sunil V Rao.;Frank W Sellke.;Garima Sharma.;Celina M Yong.;Brittany A Zwischenberger.
来源: Circulation. 2022年145卷3期e18-e114页 4817. Long-Term Follow-Up of DANISH (The Danish Study to Assess the Efficacy of ICDs in Patients With Nonischemic Systolic Heart Failure on Mortality).
作者: Adelina Yafasova.;Jawad H Butt.;Marie B Elming.;Jens C Nielsen.;Jens Haarbo.;Lars Videbæk.;Line L Olesen.;Flemming H Steffensen.;Niels E Bruun.;Hans Eiskjær.;Axel Brandes.;Anna M Thøgersen.;Kenneth Egstrup.;Finn Gustafsson.;Christian Hassager.;Jesper H Svendsen.;Dan E Høfsten.;Christian Torp-Pedersen.;Steen Pehrson.;Jens J Thune.;Lars Køber.
来源: Circulation. 2022年145卷6期427-436页
DANISH (The Danish Study to Assess the Efficacy of Implantable Cardioverter Defibrillators [ICDs] in Patients With Nonischemic Systolic Heart Failure on Mortality) found that primary-prevention ICD implantation was not associated with an overall survival benefit in patients with nonischemic systolic heart failure during a median follow-up of 5.6 years, although there was a beneficial effect on all-cause mortality in patients ≤70 years. This study presents an additional 4 years of follow-up data from DANISH.
4818. Use of Extracorporeal Membrane Oxygenation as Bridge to Replacement Therapies in Cardiogenic Shock: Insights From the Extracorporeal Life Support Organization.
作者: Ioannis Mastoris.;Joseph E Tonna.;Jinxiang Hu.;Andrew J Sauer.;Nicholas A Haglund.;Peter Rycus.;Yu Wang.;William J Wallisch.;Travis O Abicht.;Matthew R Danter.;Ryan J Tedford.;James C Fang.;Zubair Shah.
来源: Circ Heart Fail. 2022年15卷1期e008777页
There has been increasing use of extracorporeal membrane oxygenation (ECMO) as bridge to heart transplant (orthotopic heart transplant [OHT]) or left ventricular assist device (LVAD) over the last decade. We aimed to provide insights on the population, outcomes, and predictors for the selection of each therapy.
4819. Determinants of Incident Atherosclerotic Cardiovascular Disease Events Among Those With Absent Coronary Artery Calcium: Multi-Ethnic Study of Atherosclerosis.
作者: Mahmoud Al Rifai.;Michael J Blaha.;Vijay Nambi.;Steven J C Shea.;Erin D Michos.;Roger S Blumenthal.;Christie M Ballantyne.;Moyses Szklo.;Philip Greenland.;Michael D Miedema.;Khurram Nasir.;Jerome I Rotter.;Xiuqing Guo.;Jie Yao.;Wendy S Post.;Salim S Virani.
来源: Circulation. 2022年145卷4期259-267页
The 2018 American Heart Association/American College of Cardiology/Multisociety cholesterol guideline states that statin therapy may be withheld or delayed among intermediate-risk individuals in the absence of coronary artery calcium (CAC=0). We evaluated whether traditional cardiovascular risk factors are associated with incident atherosclerotic cardiovascular disease (ASCVD) events among individuals with CAC=0 over long-term follow-up.
4820. An International Multicenter Cohort Study on β-Blockers for the Treatment of Symptomatic Children With Catecholaminergic Polymorphic Ventricular Tachycardia.
作者: Puck J Peltenburg.;Dania Kallas.;Johan M Bos.;Krystien V V Lieve.;Sonia Franciosi.;Thomas M Roston.;Isabelle Denjoy.;Katrina B Sorensen.;Seiko Ohno.;Ferran Roses-Noguer.;Takeshi Aiba.;Alice Maltret.;Martin J LaPage.;Joseph Atallah.;John R Giudicessi.;Sally-Ann B Clur.;Nico A Blom.;Michael Tanck.;Fabrice Extramiana.;Koichi Kato.;Julien Barc.;Martin Borggrefe.;Elijah R Behr.;Georgia Sarquella-Brugada.;Jacob Tfelt-Hansen.;Esther Zorio.;Heikki Swan.;Janneke A E Kammeraad.;Andrew D Krahn.;Andrew Davis.;Frederic Sacher.;Peter J Schwartz.;Jason D Roberts.;Jonathan R Skinner.;Maarten P van den Berg.;Prince J Kannankeril.;Fabrizio Drago.;Tomas Robyns.;Kristina Haugaa.;Terezia Tavacova.;Christopher Semsarian.;Jan Till.;Vincent Probst.;Ramon Brugada.;Wataru Shimizu.;Minoru Horie.;Antoine Leenhardt.;Michael J Ackerman.;Shubhayan Sanatani.;Christian van der Werf.;Arthur A M Wilde.
来源: Circulation. 2022年145卷5期333-344页
Symptomatic children with catecholaminergic polymorphic ventricular tachycardia (CPVT) are at risk for recurrent arrhythmic events. β-Blockers decrease this risk, but studies comparing individual β-blockers in sizeable cohorts are lacking. We aimed to assess the association between risk for arrhythmic events and type of β-blocker in a large cohort of symptomatic children with CPVT.
|