Lancet[journal] 检索结果

4441. Etrasimod as induction and maintenance therapy for ulcerative colitis (ELEVATE): two randomised, double-blind, placebo-controlled, phase 3 studies.

作者: William J Sandborn.;Séverine Vermeire.;Laurent Peyrin-Biroulet.;Marla C Dubinsky.;Julian Panes.;Andres Yarur.;Timothy Ritter.;Filip Baert.;Stefan Schreiber.;Sheldon Sloan.;Fabio Cataldi.;Kevin Shan.;Christopher J Rabbat.;Michael Chiorean.;Douglas C Wolf.;Bruce E Sands.;Geert D'Haens.;Silvio Danese.;Martina Goetsch.;Brian G Feagan.
来源: Lancet. 2023年401卷10383期1159-1171页

Etrasimod, a once-daily, oral, sphingosine 1-phosphate (S1P) receptor modulator that selectively activates S1P receptor subtypes 1, 4, and 5, with no detectable activity on S1P2,3, is in development for the treatment of immune-mediated diseases, including ulcerative colitis. In these two phase 3 trials, we aimed to evaluate the safety and efficacy of etrasimod in adult patients with moderately to severely active ulcerative colitis.

4442. Effectiveness of a non-physician community health-care provider-led intensive blood pressure intervention versus usual care on cardiovascular disease (CRHCP): an open-label, blinded-endpoint, cluster-randomised trial.

作者: Jiang He.;Nanxiang Ouyang.;Xiaofan Guo.;Guozhe Sun.;Zhao Li.;Jianjun Mu.;Dao Wen Wang.;Lixia Qiao.;Liying Xing.;Guocheng Ren.;Chunxia Zhao.;Ruihai Yang.;Zuyi Yuan.;Chang Wang.;Chuning Shi.;Songyue Liu.;Wei Miao.;Guangxiao Li.;Chung-Shiuan Chen.;Yingxian Sun.; .
来源: Lancet. 2023年401卷10380期928-938页

Effectiveness of a non-physician community health-care provider-led intensive blood pressure intervention on cardiovascular disease has not been established. We aimed to test the effectiveness of such an intervention compared with usual care on risk of cardiovascular disease and all-cause death among individuals with hypertension.

4443. Improving cardiovascular health in rural China and beyond.

作者: Lijing L Yan.;Biraj M Karmacharya.
来源: Lancet. 2023年401卷10380期879-881页

4444. Confronting the evolution and expansion of anti-vaccine activism in the USA in the COVID-19 era.

作者: Richard M Carpiano.;Timothy Callaghan.;Renee DiResta.;Noel T Brewer.;Chelsea Clinton.;Alison P Galvani.;Rekha Lakshmanan.;Wendy E Parmet.;Saad B Omer.;Alison M Buttenheim.;Regina M Benjamin.;Arthur Caplan.;Jad A Elharake.;Lisa C Flowers.;Yvonne A Maldonado.;Michelle M Mello.;Douglas J Opel.;Daniel A Salmon.;Jason L Schwartz.;Joshua M Sharfstein.;Peter J Hotez.
来源: Lancet. 2023年401卷10380期967-970页

4445. The sphingosine-1-phosphate receptor agonist etrasimod in ulcerative colitis.

作者: Raja Atreya.;Markus F Neurath.
来源: Lancet. 2023年401卷10383期1132-1133页

4446. Seeking solutions to global drugs shortages.

作者: Ferry Biedermann.
来源: Lancet. 2023年401卷10378期720-721页

4447. Experts warn over potential for measles in Ukraine.

作者: Ed Holt.
来源: Lancet. 2023年401卷10378期719页

4448. New leadership for Gavi.

作者: John Zarocostas.
来源: Lancet. 2023年401卷10378期718页

4449. Human epidermal growth factor receptor 2-positive metastatic gastric cancer in complete sustained remission with trastuzumab.

作者: Denis O'Mahony.;Stephen P Power.;Derek G Power.
来源: Lancet. 2023年401卷10378期772页

4450. GBD 2019 study informs industry yet crucial questions remain unanswered - Authors' reply.

作者: Jeffrey D Stanaway.;Simon I Hay.;Christopher J L Murray.; .
来源: Lancet. 2023年401卷10378期731-732页

4451. GBD 2019 study informs industry yet crucial questions remain unanswered.

作者: Nick Allen.; .
来源: Lancet. 2023年401卷10378期731页

4452. GBD 2019 study informs industry yet crucial questions remain unanswered.

作者: John Thorley.
来源: Lancet. 2023年401卷10378期730页

4453. GBD 2019 study informs industry yet crucial questions remain unanswered.

作者: Tim Rycroft.
来源: Lancet. 2023年401卷10378期729-730页

4454. When was mpox a public health emergency?

作者: Stephen A Hoption Cann.
来源: Lancet. 2023年401卷10378期729页

4455. The human rights to water and sanitation, gender equality, and the State.

作者: Léo Heller.
来源: Lancet. 2023年401卷10378期728页

4456. The resurgence of dengue epidemic and climate change in India.

作者: Nitish Mondal.
来源: Lancet. 2023年401卷10378期727-728页

4457. Offline: The willing versus the legitimate.

作者: Richard Horton.
来源: Lancet. 2023年401卷10378期717页

4458. A decisive moment for The World Bank.

作者: The Lancet.
来源: Lancet. 2023年401卷10378期705页

4459. Implausible algorithm output in UK liver transplantation allocation scheme: importance of transparency.

作者: Antony Attia.;Ian A Rowe.;Ewen M Harrison.;Tim Gordon-Walker.;Ben M Stutchfield.
来源: Lancet. 2023年401卷10380期911-912页

4460. Addressing the effects of the earthquakes on Türkiye's health-care system.

作者: Olivier Uwishema.
来源: Lancet. 2023年401卷10378期727页

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