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4041. SPOCK1 and POSTN are valuable prognostic biomarkers and correlate with tumor immune infiltrates in colorectal cancer.
作者: Caiqin Gan.;Mengting Li.;Yuanyuan Lu.;Ganjing Peng.;Wenjie Li.;Haizhou Wang.;Yanan Peng.;Qian Hu.;Wanhui Wei.;Fan Wang.;Lan Liu.;Qiu Zhao.
来源: BMC Gastroenterol. 2023年23卷1期4页
Immune cells and stromal cells in the tumor microenvironment play a vital role in the progression of colorectal cancer (CRC). The study aimed to screen valuable prognostic biomarkers in CRC based on stromal and immune scores.
4049. Low thyroid function is associated with an increased risk of advanced fibrosis in patients with metabolic dysfunction-associated fatty liver disease.
作者: Hong Fan.;Lili Li.;Zhenqiu Liu.;Pengyan Zhang.;Sheng Wu.;Xinyu Han.;Xingdong Chen.;Chen Suo.;Liou Cao.;Tiejun Zhang.
来源: BMC Gastroenterol. 2023年23卷1期3页
Observational studies showed that low thyroid function may perturb liver function. We aimed to evaluate the association of low thyroid function with both metabolic dysfunction-associated fatty liver disease (MAFLD) and advanced hepatic fibrosis.
4050. PLAGL1 is associated with prognosis and cell proliferation in pancreatic adenocarcinoma.
作者: Xing Liang.;Zhiping Fu.;Liang Tang.;Minghui Zheng.;Danlei Chen.;Anan Liu.;Ligang Shi.;Linhua Yang.;Chenghao Shao.;Xiaoqiang Dong.
来源: BMC Gastroenterol. 2023年23卷1期2页
Emerging evidence has shown the crucial roles of pleomorphic adenoma gene (PLAG) family genes in multiple cancers. However, their functions and mechanisms in pancreatic adenocarcinoma (PAAD) remain poorly understood.
4052. Establishment and evaluation of an early prediction model of hepatorenal syndrome in patients with decompensated hepatitis B cirrhosis.
作者: Shouhao Wang.;Zhewen Zhou.;Chengan Xu.;Hanzhu Chen.;Wenya Ren.;Xingdi Yang.;Qiaoqiao Yin.;Wei Zheng.;Hongying Pan.
来源: BMC Gastroenterol. 2023年23卷1期1页
In China, hepatorenal syndrome is a serious complication in the decompensated stage of hepatitis B cirrhosis, which requires early clinical intervention, so the early diagnosis of hepatorenal syndrome is crucial. This study establishes a new predictive model based on serum biomarkers for the early diagnosis of hepatorenal syndrome.
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