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397. Transfusion of Fresh Frozen Plasma and Platelets in Critically Ill Adults: An American College of Chest Physicians Clinical Practice Guideline.
作者: Angel Coz Yataco.;Israa Soghier.;Paul C Hébert.;Emilie Belley-Cote.;Margaret Disselkamp.;David Flynn.;Karin Halvorson.;Jonathan M Iaccarino.;Wendy Lim.;Christina C Lindenmeyer.;Peter J Miller.;Kevin O'Neil.;Kathryn M Pendleton.;Lisa Vande Vusse.;Daniel R Ouellette.
来源: Chest. 2025年168卷3期661-676页
Platelets and fresh frozen plasma (FFP) are frequently administered to critically ill patients. Considering the variability in indications and thresholds guiding these transfusions, a comprehensive review of current evidence was conducted to provide guidance to critical care practitioners. This American College of Chest Physicians guideline examined the literature on platelet transfusions in critically ill patients with thrombocytopenia, with and without active bleeding, as well as data on prophylactic platelet and FFP transfusions for common procedures in the critical care setting.
399. Association Between Preserved Ratio Impaired Spirometry and COPD With Coronary Artery Calcification Measured by Coronary CT Scan.
作者: Purnadeo N Persaud.;Lauren S Munoz Tremblay.;Yanjun Wu.;Peter Oro.;Daniel A Culver.;James K Stoller.;Xiaofeng Wang.;Raul Seballos.;Richard H Cartabuke.;Trishul Siddharthan.;Vickram Tejwani.
来源: Chest. 2025年168卷2期410-414页 400. Importance of Preserved Ratio Impaired Spirometry as a Risk Factor for Development of COPD, Also in Those Who Do Not Smoke.
作者: Helena Backman.;Tomi Myrberg.;Linnea Hedman.;Caroline Stridsman.;Eva Rönmark.;Anne Lindberg.
来源: Chest. 2025年168卷1期83-94页
COPD is largely underdiagnosed. Active identification of cases is crucial to establish preventive measures before manifestation of clinical disease. The significance of different spirometric patterns preceding COPD, especially preserved ratio impaired spirometry (PRISm), has been highlighted but remains unclear.
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