当前位置: 首页 >> 检索结果
321. Gut microbiome-metabolome dysregulation in systemic sclerosis: a multi-omics study.
作者: Qi-Cen Yao.;Da-Ya Zhang.;Yi-Ping Du.;Chen Chen.;Yan-Ting Lv.;Da Li.;Yi-Xi Xing.;Xia-Yu Xu.;Qian-Qi Lin.;Wen-Feng Tan.;Fei-Hu Bai.
来源: Rheumatology (Oxford). 2026年65卷1期
The interplay between the gut microbiome (GM), plasma metabolites and systemic sclerosis (SSc) has not been systematically studied. We hypothesized that disruption at the GM-metabolome interface contributes to the pathogenesis of SSc. This study aims to investigate the faecal microbiome composition and plasma metabolite profiles in SSc patients.
323. Lengthened telomere length in peripheral blood leukocytes in patients with rheumatoid arthritis complicated with airway disease.
作者: Takashi Higuchi.;Shomi Oka.;Kota Shimada.;Shinichiro Tsunoda.;Satoshi Ito.;Misuzu Fujimori.;Tadashi Nakamura.;Michita Suzuki.;Koichiro Saisho.;Satoshi Shinohara.;Toshihiro Matsui.;Kiyoshi Migita.;Shouhei Nagaoka.;Shigeto Tohma.;Hiroshi Furukawa.
来源: BMC Rheumatol. 2025年10卷1期6页
Patients with rheumatoid arthritis (RA) frequently have complications including chronic lung diseases (CLDs) consisting of airway disease (AD) or interstitial lung disease (ILD) that confer a poor prognosis. Peripheral blood leukocyte telomere length is shortened in RA with ILD. Previous studies reported rare variants in telomerase genes that were deleterious were more frequent in RA with ILD compared with controls. However, these studies were conducted in European populations. Here, we investigated associations of telomere length with ILD or AD in Japanese RA.
324. Overlapping macrophage immune profiles in polymyalgia rheumatica and giant cell arteritis.
作者: Anqi Zhang.;William F Jiemy.;Yannick van Sleen.;Shuang Xu.;Maria Sandovici.;Wayel H Abdulahad.;Arjan Diepstra.;Sandra Hein.;Jacoba C Graver.;Peter Heeringa.;Bhaskar Dasgupta.;Elisabeth Brouwer.;Kornelis S M van der Geest.
来源: Rheumatology (Oxford). 2026年65卷2期
Polymyalgia rheumatica (PMR) and giant cell arteritis (GCA) are closely related chronic inflammatory diseases in which macrophages play a central role in the pathogenesis. This study compared macrophage-related immune profiles in subacromial bursal tissues affected by PMR and temporal arteries affected by GCA to identify shared therapeutic targets.
325. Results from a pilot study of dusquetide for the treatment of aphthous ulcers associated with Behçet's syndrome.
作者: Oreola Donini.;Bercemhan Sulu.;Christopher Pullion.;Adam Rumage.;Richard Straube.;Christopher Schaber.;Gülen Hatemi.
来源: Rheumatology (Oxford). 2026年65卷2期
The study was designed to obtain a preliminary assessment of the safety and efficacy of SGX945 (dusquetide) for the treatment of aphthous oral and genital ulcers in Behçet's syndrome.
326. Real-world experience of anifrolumab in 30 patients with refractory DM: a multicentre-multidisciplinary retrospective study.
作者: Míriam Retuerto-Guerrero.;Clara Moriano Morales.;Ana Pareja-Martínez.;Natalia Molina-Esteban.;Jose Puig-Buendia.;Concepción Postigo Llorente.;Ana Lopez-Ceron Cofiño.;Julia Martínez-Barrio.;Paola Vidal-Montal.;Elena Sendagorta Cudos.;Luisa Martos Cabrera.;Guillermo González Arribas.;Jaime Calvo Alén.;Juan Ramón De Dios Jiménez de Aberasturi.;Juan María Blanco Madrigal.;Javier Bachiller Corral.;Alejandro Claudio Oliva.;Paloma Vela Casasempere.;Maria Castellanos Gonzalez.;Maria Concepción Fito Manteca.;Tania Marusia Capusan.;Carmen Ordás Calvo.;Daniel Ramos Rodríguez.;Alejandro Sanchez Herrero.;Luis Ortega-Valín.;Elvira Díez Álvarez.
来源: Rheumatology (Oxford). 2026年65卷2期
To assess real-world outcomes of anifrolumab (ANI) in refractory systemic DM.
329. Prevalence, distribution and associations of the scleroderma capillaroscopic patterns: new insights from the Italian SPRING-SIR registry.
作者: Rossella De Angelis.;Clodoveo Ferri.;Edoardo Cipolletta.;Valeria Riccieri.;Marco Di Battista.;Gianluigi Bajocchi.;Silvia Bellando-Randone.;Cosimo Bruni.;Martina Orlandi.;Giovanni Zanframundo.;Roberta Foti.;Giovanna Cuomo.;Alarico Ariani.;Edoardo Rosato.;Gemma Lepri.;Francesco Girelli.;Elisabetta Zanatta.;Silvia Laura Bosello.;Ilaria Cavazzana.;Francesca Ingegnoli.;Maria De Santis.;Fabio Cacciapaglia.;Giuseppe Murdaca.;Giuseppina Abignano.;Giorgio Pettiti.;Alessandra Della Rossa.;Maurizio Caminiti.;Anna Maria Iuliano.;Giovanni Ciano.;Lorenzo Beretta.;Gianluca Bagnato.;Ennio Lubrano.;Ilenia De Andres.;Luca Idolazzi.;Marta Saracco.;Cecilia Agnes.;Corrado Campochiaro.;Marco Fornaro.;Federica Lumetti.;Amelia Spinella.;Emanuele Cocchiara.;Giacomo De Luca.;Veronica Codullo.;Elisa Visalli.;Carlo Iandoli.;Antonietta Gigante.;Greta Pellegrino.;Erika Pigatto.;Maria Grazia Lazzaroni.;Enrico De Lorenzis.;Francesca Motta.;Antonio Tonutti.;Gianna Mennillo.;Giuseppa Pagano-Mariano.;Federica Furini.;Licia Vultaggio.;Simone Parisi.;Clara Lisa Peroni.;Gerolamo Bianchi.;Enrico Fusaro.;Gian Domenico Sebastiani.;Marcello Govoni.;Salvatore D'Angelo.;Franco Cozzi.;Franco Franceschini.;Serena Guiducci.;Dilia Giuggioli.;Lorenzo Dagna.;Andrea Doria.;Carlo Salvarani.;Florenzo Iannone.;Marco Matucci-Cerinic.; .
来源: Rheumatology (Oxford). 2026年65卷1期
To assess the relationship between disease duration and the prevalence/distribution of nailfold videocapillaroscopy (NVC) patterns, named according to the current classification as 'early', 'active' and 'late', in a large cohort of systemic sclerosis (SSc) patients.
331. Diffuse alveolar haemorrhage in antiphospholipid syndrome: a French series of 26 patients.
作者: Vincent Grobost.;Mélanie Ramos.;Cécile Yelnik.;Marie De Antonio.;Nathalie Morel.;Jean-François Viallard.;Eric Hachulla.;Marc André.;Anne-Marie Milesi Lecat.;Sébastien Trouillier.;Maxime Samson.;Christian Lavigne.;Aurelien Lebreton.;Marc Lambert.;Marc Ruivard.;Nathalie Costedoat-Chalumeau.
来源: Rheumatology (Oxford). 2026年65卷3期
Diffuse alveolar haemorrhage (DAH) is a rare and poorly understood manifestation of antiphospholipid (AP) syndrome (APS). This study describes the clinical presentation, treatment and prognosis of DAH in APS with or without catastrophic APS (CAPS).
332. Comment on: How early is early for JIA? Insights from the infantile-onset juvenile idiopathic arthritis patients of the PERA research group cohort: reply.
作者: Kubra Ozturk.;Tuncay Aydin.;Gulcan Ozomay Baykal.;Esra Baglan.;Hulya Kose.;Hakan Kisaoglu.;Deniz Gezgin Yildirim.;Fatma Gul Demirkan.;Gulcin Otar Yener.;Mustafa Çakan.;Belde Kasap Demir.;Hatice Adiguzel Dundar.;Gulsah Kilbas.;Hafize Emine Sonmez.;Serkan Turkucar.;Balahan Bora.;Selcuk Yuksel.;Nuray Aktay Ayaz.;Sevcan Bakkaloglu.;Mukaddes Kalyoncu.;Sara Sebnem Kilic.;Semanur Ozdel.;Betul Sozeri.;Erbil Unsal.
来源: Rheumatology (Oxford). 2026年65卷2期 333. Systemic inflammation in gout and the impact of treat-to-target urate-lowering therapy.
作者: Austin M Wheeler.;Tanner J Ourada.;Spencer Q Jones.;Michael J Duryee.;Bryant R England.;Richard J Reynolds.;James R O'Dell.;Jeff Newcomb.;Michael H Pillinger.;Robert Terkeltaub.;Ryan Ferguson.;Mary Brophy.;Brian LaMoreaux.;Tony R Merriman.;Ted R Mikuls.
来源: Rheumatology (Oxford). 2025年
We tested the hypotheses that individuals with gout would have distinct circulating inflammatory biomarker patterns compared with non-gout controls and that these differences would be attenuated with highly-effective urate-lowering therapy (ULT).
334. Loss of antiphospholipid antibody positivity decreases the risk of recurrent thrombosis in thrombotic antiphospholipid syndrome.
作者: Pedro Gaspar.;Ana Rita Cruz-Machado.;Ana Mafalda Abrantes.;Filipa Costa.;Inês Parreira.;Ana Rita Lopes.;Ryan Costa-Silva.;Ana Teodósio Chícharo.;Joana Rosa Martins.;João Pedro Marques.;Diogo Santos.;Vasco C Romão.;Luis Graca.;João E Fonseca.
来源: Rheumatology (Oxford). 2026年65卷1期
To establish the predictive value of antiphospholipid antibody (aPL) negativization on recurrent thrombosis in thrombotic antiphospholipid syndrome (APS).
337. Prevalence, clinical associations and outcomes of pericarditis in systemic lupus erythematosus: insights from the University of Toronto Lupus Clinic.
作者: Pankti Mehta.;Fadi Kharouf.;Virginia Carrizo-Abarza.;Qixuan Li.;Shadi Akhtari.;Paula Harvey.;Oluwatosin Osuntokun.;Laura P Whittall Garcia.;Dafna D Gladman.;Zahi Touma.
来源: Rheumatology (Oxford). 2026年65卷2期
Pericarditis is an important clinical feature in the classification criteria and disease activity indices in SLE. We aimed to study the prevalence, associations and outcomes of pericarditis in SLE.
338. Sirolimus to treat chronic uveitis in PTEN hamartoma tumor syndrome: experience of a target therapy customized on specific disease pathway.
作者: Laura Gatti.;Cinzia de Libero.;Edoardo Marrani.;Ilaria Pagnini.;Maria Vincenza Mastrolia.;Gabriele Simonini.;Ilaria Maccora.
来源: Rheumatology (Oxford). 2026年65卷1期 339. Predictors and long-term impact of sustained complete renal response in lupus nephritis patients over a median 10-year follow-up.
作者: Ioannis E Michelakis.;Eleni Kapsia.;John N Boletis.;Smaragdi Marinaki.;Petros P Sfikakis.;Maria G Tektonidou.
来源: Rheumatology (Oxford). 2026年65卷3期
Complete renal response (CRR) is a primary goal in lupus nephritis (LN) management. We examined the prevalence and predictors of sustained CRR (sCRR) and long-term outcomes.
|