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3341. Treatment of acute mesenteric ischemia between 2010 and 2020 - a German nation-wide study.
作者: Stefanie Bette.;Osama Habeeballah.;Jan H Luitjens.;Thomas Kroencke.;Christian Scheurig-Muenkler.;Josua A Decker.
来源: BMC Gastroenterol. 2023年23卷1期300页
Aim of this study was to analyze long-term trends of hospitalizations, treatment regimen and in-hospital mortality of in-patients with acute mesenteric ischemia (AMI) over the past decade and effects of the SARS-CoV2-pandemic.
3342. Prevalence of vomiting and nausea and associated factors after chronic and acute gluten exposure in celiac disease.
作者: Iida Ahonen.;Pilvi Laurikka.;Sara Koskimaa.;Heini Huhtala.;Katri Lindfors.;Katri Kaukinen.;Kalle Kurppa.;Laura Kivelä.
来源: BMC Gastroenterol. 2023年23卷1期301页
Vomiting and nausea seem to be relatively specific symptoms related to gluten ingestion in treated celiac disease. However, the overall prevalence and associated factors of these symptoms after chronic gluten exposure at celiac disease diagnosis and acute re-exposure during gluten challenge remain obscure.
3343. The influence of muscle performance and fatigue on prognosis in patients with compensated liver disease.
作者: Ulrika Ekerfors.;Magnus Simrén.;Hanns-Ulrich Marschall.;Daghan Demir.;Axel Josefsson.
来源: BMC Gastroenterol. 2023年23卷1期302页
Poor muscle function is associated with a negative prognosis in advanced liver disease but the impact in compensated chronic liver disease is unknown. Similar prognostic uncertainty applies to fatigue. We aimed to assess the prognostic value of muscle performance and fatigue in a cohort of patients with compensated chronic liver disease.
3344. Is empiric proton pump inhibition in patients with symptoms of extraesophageal gastroesophageal reflux justified?
The prevalence of gastroesophageal reflux disease (GERD) has had a marked increase in Western countries with a paralleling interest in extraesophageal (EE) manifestations of GERD, including laryngopharyngeal reflux (LPR). There are considerable differences in clinical practice between gastroenterologists, otolaryngologists and pulmonologists.
3345. Multicentre prospective study to evaluate effectiveness and safety of gel-forming and hyaluronic-acid containing chewable tablets as add-on treatment in patients with gastroesophageal reflux disease (GERD) symptoms and unsatisfying proton pump inhibitor therapy.
作者: Manfred Gross.;Dennis Neuschwander.;Lisa Steffens.;Jörn Thomsen.;Kristina Röschmann-Doose.
来源: BMC Gastroenterol. 2023年23卷1期304页
Gastroesophageal reflux disease (GERD) is a common disease which in the majority of patients is treated with proton pump inhibitors (PPI). However, up to 45% of the patients remain symptomatic on a standard dose of PPI. This study investigated the effectiveness and safety of an add-on therapy with the gel-forming chewable tablet Sobrade® in patients unsatisfied with PPI treatment. The bioadhesive gel covers the oesophagus and thereby protects the mucosa from reflux events.
3347. Cystic tumor ablation with different concentrations of lauromacrogol solution in an animal model.
作者: Fei Gao.;Huikai Li.;Xiuxue Feng.;Chen DU.;Ke Han.;Ningli Chai.;Enqiang Linghu.
来源: Minerva Gastroenterol (Torino). 2024年70卷4期422-429页
Lauromacrogol, as a sclerosing agent, can induce aseptic inflammation and fibrous tissue proliferation to achieve sclerotherapy. Lauromacrogol is widely used not only for vascular sclerotherapy but also for the treatment of different cystic tumors. To evaluate the efficacy and safety of cystic tumor ablation with different concentrations of lauromacrogol solution in a rat endometriosis model, and explore the advantages and disadvantages of this model in simulating pancreatic cystic neoplasm.
3348. Transhepatectomy combined with arterial chemoembolization and transcatheter arterial chemoembolization in the treatment of hepatocellular carcinoma: a clinical prognostic analysis.
作者: Xin Liu.;Haodong Li.;Fei Wang.;Ke Su.;Bingsheng He.;Jie He.;Jiaqi Zhong.;Yunwei Han.;Zhenjiang Li.
来源: BMC Gastroenterol. 2023年23卷1期299页
The prognosis of patients undergoing hepatectomy combined with transarterial chemoembolization (TACE) and TACE alone was examined in order to better understand the role of hepatectomy in the treatment of hepatocellular carcinoma (HCC). In this work, we also created a model and investigated the variables influencing overall survival (OS) in HCC patients.
3349. The efficacy of non-anesthesiologist-administered propofol sedation with a target-controlled infusion system during double-balloon endoscopic retrograde cholangiopancreatography.
作者: Kazuya Miyamoto.;Kazuyuki Matsumoto.;Taisuke Obata.;Ryosuke Sato.;Akihiro Matsumi.;Kosaku Morimoto.;Taiji Ogawa.;Hiroyuki Terasawa.;Yuki Fujii.;Tatsuhiro Yamazaki.;Daisuke Uchida.;Shigeru Horiguchi.;Koichiro Tsutsumi.;Hironari Kato.;Motoyuki Otsuka.
来源: BMC Gastroenterol. 2023年23卷1期296页
The sedation method used during double-balloon endoscopic retrograde cholangiopancreatography (DB-ERCP) differs among countries and/or facilities, and there is no established method. This study aimed to evaluate the efficacy of non-anesthesiologist-administered propofol (NAAP) sedation using a target-controlled infusion (TCI) system during DB-ERCP.
3350. Relapse rate and predictors of relapse after cessation of glucocorticoid maintenance therapy in type 1 autoimmune pancreatitis: a multicenter retrospective study.
作者: Yusuke Kiyoshita.;Yasutaka Ishii.;Masahiro Serikawa.;Keiji Hanada.;Tamito Sasaki.;Yoshifumi Fujimoto.;Atsushi Yamaguchi.;Ken Hirao.;Bunjiro Noma.;Tomoyuki Minami.;Akihito Okazaki.;Masanobu Yukutake.;Teruo Mouri.;Tomofumi Tsuboi.;Yumiko Tatsukawa.;Shinya Nakamura.;Tetsuro Hirano.;Juri Ikemoto.;Sho Saeki.;Yosuke Tamura.;Sayaka Miyamoto.;Masaru Furukawa.;Kazuki Nakmura.;Yumiko Yamashita.;Noriaki Iijima.;Shiro Oka.
来源: BMC Gastroenterol. 2023年23卷1期295页
Type 1 autoimmune pancreatitis responds well to glucocorticoid therapy with a high remission rate. Moreover, glucocorticoid maintenance therapy can help prevent relapse. However, the relapse rate following cessation of long-term glucocorticoid therapy is unknown. The aim of this study was to clarify the relapse rate and predictors of relapse following long-term glucocorticoid therapy cessation.
3351. Evaluation of ITGB1 expression as a predictor of the therapeutic effects of immune checkpoint inhibitors in gastric cancer.
Gastric cancer (CC) is a disease with high incidence and mortality rate. Immunotherapy is an important method for gastric cancer while lack of effective predictor. Integrins play an important role in the development. We aimed to explore the predictive value of β1 integrin (ITGB1) as a predictor of immunnotherapy in gastric cancer.
3352. Oncologic relevance of genetic alterations in sporadic synchronous and solitary colorectal cancer: a retrospective multicenter study.
作者: Il Tae Son.;Minsung Kim.;Bo Young Oh.;Min Jeong Kim.;Sang Nam Yoon.;Jun Ho Park.;Byung Chun Kim.;Jong Wan Kim.
来源: BMC Gastroenterol. 2023年23卷1期297页
Oncologic impact of genetic alteration across synchronous colorectal cancer (CRC) still remains unclear. This study aimed to compare the oncologic relevance according to genetic alteration between synchronous and solitary CRC with performing systematic review.
3354. Genetic Defect in Submucosal Gland-Associated Caveolin-3: A New Paradigm in Esophageal Adenocarcinoma Risk.
作者: Katherine S Garman.;Biswa P D Purkayastha.;Joyce A Hogue.;Ryan Fecteau.; .;Kishore Guda.;Amitabh Chak.
来源: Gastroenterology. 2023年165卷6期1561-1564.e3页 3357. Guselkumab in Patients With Moderately to Severely Active Ulcerative Colitis: QUASAR Phase 2b Induction Study.
作者: Laurent Peyrin-Biroulet.;Jessica R Allegretti.;David T Rubin.;Brian Bressler.;Matthew Germinaro.;Kuan-Hsiang Gary Huang.;Nicole Shipitofsky.;Hongyan Zhang.;Rebbecca Wilson.;Chenglong Han.;Brian G Feagan.;William J Sandborn.;Julian Panés.;Tadakazu Hisamatsu.;Gary R Lichtenstein.;Bruce E Sands.;Axel Dignass.; .
来源: Gastroenterology. 2023年165卷6期1443-1457页
The QUASAR Phase 2b Induction Study evaluated the efficacy and safety of guselkumab, an interleukin-23p19 subunit antagonist, in patients with moderately to severely active ulcerative colitis (UC) with prior inadequate response and/or intolerance to corticosteroids, immunosuppressants, and/or advanced therapy.
3358. Risk of Cancer and Mortality in Peutz-Jeghers Syndrome and Juvenile Polyposis Syndrome-A Nationwide Cohort Study With Matched Controls.
作者: Anne Marie Jelsig.;Laus Wullum.;Tine Plato Kuhlmann.;Lilian Bomme Ousager.;Johan Burisch.;John Gásdal Karstensen.
来源: Gastroenterology. 2023年165卷6期1565-1567.e2页 |