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2121. COVID-19 Vaccination Effectiveness Against Infection or Death in a National U.S. Health Care System : A Target Trial Emulation Study.
作者: George N Ioannou.;Emily R Locke.;Ann M O'Hare.;Amy S B Bohnert.;Edward J Boyko.;Denise M Hynes.;Kristin Berry.
来源: Ann Intern Med. 2022年175卷3期352-361页
Little is known about real-world COVID-19 vaccine effectiveness (VE) in racially and ethnically diverse, elderly populations with high comorbidity burden.
2122. Firearm Purchasing During the COVID-19 Pandemic: Results From the 2021 National Firearms Survey.
The surge in background checks beginning in March 2020 suggested an acceleration in firearm purchases. Little was known about the people who bought these guns.
2123. Responses to a Neutralizing Monoclonal Antibody for Hospitalized Patients With COVID-19 According to Baseline Antibody and Antigen Levels : A Randomized Controlled Trial.
作者: .;Jens D Lundgren.;Birgit Grund.;Christina E Barkauskas.;Thomas L Holland.;Robert L Gottlieb.;Uriel Sandkovsky.;Samuel M Brown.;Kirk U Knowlton.;Wesley H Self.;D Clark Files.;Mamta K Jain.;Thomas Benfield.;Michael E Bowdish.;Bradley G Leshnower.;Jason V Baker.;Jens-Ulrik Jensen.;Edward M Gardner.;Adit A Ginde.;Estelle S Harris.;Isik S Johansen.;Norman Markowitz.;Michael A Matthay.;Lars Østergaard.;Christina C Chang.;Anna L Goodman.;Weizhong Chang.;Robin L Dewar.;Norman P Gerry.;Elizabeth S Higgs.;Helene Highbarger.;Daniel D Murray.;Thomas A Murray.;Ven Natarajan.;Roger Paredes.;Mahesh K B Parmar.;Andrew N Phillips.;Cavan Reilly.;Adam W Rupert.;Shweta Sharma.;Kathryn Shaw-Saliba.;Brad T Sherman.;Marc Teitelbaum.;Deborah Wentworth.;Huyen Cao.;Paul Klekotka.;Abdel G Babiker.;Victoria J Davey.;Annetine C Gelijns.;Virginia L Kan.;Mark N Polizzotto.;B Taylor Thompson.;H Clifford Lane.;James D Neaton.
来源: Ann Intern Med. 2022年175卷2期234-243页
In a randomized, placebo-controlled, clinical trial, bamlanivimab, a SARS-CoV-2-neutralizing monoclonal antibody, given in combination with remdesivir, did not improve outcomes among hospitalized patients with COVID-19 based on an early futility assessment.
2128. Update Alert 3: Ventilation Techniques and Risk for Transmission of Coronavirus Disease, Including COVID-19.
作者: Giovanna Elsa Ute Muti-Schüenemann.;Wojciech Szczeklik.;Karla Solo.;Joanne Khabsa.;Rebecca Thomas.;Ewa Borowiack.;Assem M Khamis.;Layal Hneiny.;Andrea Darzi.;Leila Harrison.;Anna Bak.;Antonio Bongnanni.;Gian Paolo Morgano.;Rosa Stalteri.;Anisa Hajizadeh.;Tamara Lotfi.;Marge Reinap.;Bram Rochwerg.;Elie A Akl.;Holger J Schünemann.
来源: Ann Intern Med. 2022年175卷1期W6-W7页 2129. Safety and Efficiency of Diagnostic Strategies for Ruling Out Pulmonary Embolism in Clinically Relevant Patient Subgroups : A Systematic Review and Individual-Patient Data Meta-analysis.
作者: Milou A M Stals.;Toshihiko Takada.;Noémie Kraaijpoel.;Nick van Es.;Harry R Büller.;D Mark Courtney.;Yonathan Freund.;Javier Galipienzo.;Grégoire Le Gal.;Waleed Ghanima.;Menno V Huisman.;Jeffrey A Kline.;Karel G M Moons.;Sameer Parpia.;Arnaud Perrier.;Marc Righini.;Helia Robert-Ebadi.;Pierre-Marie Roy.;Maarten van Smeden.;Phil S Wells.;Kerstin de Wit.;Geert-Jan Geersing.;Frederikus A Klok.
来源: Ann Intern Med. 2022年175卷2期244-255页
How diagnostic strategies for suspected pulmonary embolism (PE) perform in relevant patient subgroups defined by sex, age, cancer, and previous venous thromboembolism (VTE) is unknown.
2130. SARS-CoV-2 Vaccine Antibody Response and Breakthrough Infection in Patients Receiving Dialysis.
作者: Shuchi Anand.;Maria E Montez-Rath.;Jialin Han.;Pablo Garcia.;LinaCel Cadden.;Patti Hunsader.;Curt Morgan.;Russell Kerschmann.;Paul Beyer.;Mary Dittrich.;Geoffrey A Block.;Glenn M Chertow.;Julie Parsonnet.
来源: Ann Intern Med. 2022年175卷3期371-378页
Whether breakthrough SARS-CoV-2 infections after vaccination are related to the level of postvaccine circulating antibody is unclear.
2132. Thiamine Supplementation in Patients With Alcohol Use Disorder Presenting With Acute Critical Illness : A Nationwide Retrospective Observational Study.
作者: Rahul D Pawar.;Lakshman Balaji.;Anne V Grossestreuer.;Garrett Thompson.;Mathias J Holmberg.;Mahmoud S Issa.;Parth V Patel.;Ryan Kronen.;Katherine M Berg.;Ari Moskowitz.;Michael W Donnino.
来源: Ann Intern Med. 2022年175卷2期191-197页
Thiamine supplementation is recommended for patients with alcohol use disorder (AUD). The authors hypothesize that critically ill patients with AUD are commonly not given thiamine supplementation.
2133. Video Teleconferencing for Disease Prevention, Diagnosis, and Treatment : A Rapid Review.
作者: Jordan Albritton.;Alexa Ortiz.;Roberta Wines.;Graham Booth.;Michael DiBello.;Stephen Brown.;Gerald Gartlehner.;Karen Crotty.
来源: Ann Intern Med. 2022年175卷2期256-266页
Video teleconferencing (VTC) as a substitute for in-person health care or as an adjunct to usual care has increased in recent years.
2134. Comparison of a Hemostatic Powder and Standard Treatment in the Control of Active Bleeding From Upper Nonvariceal Lesions : A Multicenter, Noninferiority, Randomized Trial.
作者: James Y W Lau.;Rapat Pittayanon.;Andrew Kwek.;Raymond S Tang.;Heyson Chan.;Rungsun Rerknimitr.;June Lee.;Tiing Leong Ang.;Bing-Yee Suen.;Yuan-Yuan Yu.;Francis K L Chan.;Joseph J Y Sung.
来源: Ann Intern Med. 2022年175卷2期171-178页
The effectiveness of the hemostatic powder TC-325 as a single endoscopic treatment for acute nonvariceal upper gastrointestinal bleeding is uncertain.
2135. WHO provides 2 conditional recommendations for casirivimab-imdevimab combination therapy in COVID-19.
Rochwerg B, Agarwal A, Siemieniuk RA, et al. Update to living WHO guideline on drugs for covid-19. BMJ. 2021;374:n2219. 34556469.
2136. Risk for Recurrent Venous Thromboembolism and Bleeding With Apixaban Compared With Rivaroxaban: An Analysis of Real-World Data.
作者: Ghadeer K Dawwas.;Charles E Leonard.;James D Lewis.;Adam Cuker.
来源: Ann Intern Med. 2022年175卷1期20-28页
Apixaban and rivaroxaban are replacing vitamin K antagonists for the treatment of venous thromboembolism (VTE) in adults; however, head-to-head comparisons remain limited.
2138. Comparing Video-Based, Telehealth-Delivered Exercise and Weight Loss Programs With Online Education on Outcomes of Knee Osteoarthritis : A Randomized Trial.
作者: Kim L Bennell.;Belinda J Lawford.;Catherine Keating.;Courtney Brown.;Jessica Kasza.;Dave Mackenzie.;Ben Metcalf.;Alexander J Kimp.;Thorlene Egerton.;Libby Spiers.;Joseph Proietto.;Priya Sumithran.;Anthony Harris.;Jonathan G Quicke.;Rana S Hinman.
来源: Ann Intern Med. 2022年175卷2期198-209页
Scalable knee osteoarthritis programs are needed to deliver recommended education, exercise, and weight loss interventions.
2139. Disparities in Dolutegravir Uptake Affecting Females of Reproductive Age With HIV in Low- and Middle-Income Countries After Initial Concerns About Teratogenicity : An Observational Study.
作者: Matthew L Romo.;Rena C Patel.;Jessie K Edwards.;John M Humphrey.;Beverly S Musick.;Caitlin Bernard.;Mercy W Maina.;Ellen Brazier.;Barbara Castelnuovo.;Jeremy Penner.;Katarzyna Wyka.;Sandra Wagner Cardoso.;Penh Sun Ly.;Cordelia Kunzekwenyika.;Claudia P Cortés.;Radoslaw Panczak.;Elizabeth A Kelvin.;Kara K Wools-Kaloustian.;Denis Nash.; .
来源: Ann Intern Med. 2022年175卷1期84-94页
The transition to dolutegravir-containing antiretroviral therapy (ART) in low- and middle-income countries (LMICs) was complicated by an initial safety signal in May 2018 suggesting that exposure to dolutegravir at conception was possibly associated with infant neural tube defects. On the basis of additional evidence, in July 2019, the World Health Organization recommended dolutegravir for all adults and adolescents living with HIV.
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