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2084. Case Series of Thrombosis With Thrombocytopenia Syndrome After COVID-19 Vaccination-United States, December 2020 to August 2021.
作者: Isaac See.;Allison Lale.;Paige Marquez.;Michael B Streiff.;Allison P Wheeler.;Naomi K Tepper.;Emily Jane Woo.;Karen R Broder.;Kathryn M Edwards.;Ruth Gallego.;Andrew I Geller.;Kelly A Jackson.;Shashi Sharma.;Kawsar R Talaat.;Emmanuel B Walter.;Imo J Akpan.;Thomas L Ortel.;Victor C Urrutia.;Shannon C Walker.;Jennifer C Yui.;Tom T Shimabukuro.;Adamma Mba-Jonas.;John R Su.;David K Shay.
来源: Ann Intern Med. 2022年175卷4期513-522页
Thrombosis with thrombocytopenia syndrome (TTS) is a potentially life-threatening condition associated with adenoviral-vectored COVID-19 vaccination. It presents similarly to spontaneous heparin-induced thrombocytopenia. Twelve cases of cerebral venous sinus thrombosis after vaccination with the Ad26.COV2.S COVID-19 vaccine (Janssen/Johnson & Johnson) have previously been described.
2085. Diagnosis and Management of Acute Left-Sided Colonic Diverticulitis: A Clinical Guideline From the American College of Physicians.
作者: Amir Qaseem.;Itziar Etxeandia-Ikobaltzeta.;Jennifer S Lin.;Nick Fitterman.;Tatyana Shamliyan.;Timothy J Wilt.; .;Carolyn J Crandall.;Thomas G Cooney.;J Thomas Cross.;Lauri A Hicks.;Michael Maroto.;Reem A Mustafa.;Adam J Obley.;Douglas K Owens.;Jeffrey Tice.;John W Williams.; .
来源: Ann Intern Med. 2022年175卷3期399-415页
The American College of Physicians (ACP) developed this guideline to provide clinical recommendations on the diagnosis and management of acute left-sided colonic diverticulitis in adults. This guideline is based on current best available evidence about benefits and harms, taken in the context of costs and patient values and preferences.
2086. The Epidemiology of Thrombosis With Thrombocytopenia Syndrome: Analogies With Heparin-Induced Thrombocytopenia.
In their article, See and colleagues reported a study of thrombosis with thrombocytopenia syndrome (TTS), also known as vaccine-induced immune thrombotic thrombocytopenia (VITT), a rare complication associated with receipt of the adenoviral-vectored COVID-19 vaccines ChAdOx1 nCoV-19 (Oxford/AstraZeneca) and Ad26.COV2.S (Janssen/Johnson & Johnson). The editorialists discuss the similarities of TTS with spontaneous heparin-induced thrombocytopenia.
2087. Diagnostic Imaging and Medical Management of Acute Left-Sided Colonic Diverticulitis : A Systematic Review.
作者: Ethan M Balk.;Gaelen P Adam.;Monika Reddy Bhuma.;Kristin J Konnyu.;Ian J Saldanha.;Michael D Beland.;Nishit Shah.
来源: Ann Intern Med. 2022年175卷3期379-387页
Clinicians need to better understand the value of computed tomography (CT) imaging and nonsurgical treatment options to manage acute left-sided colonic diverticulitis.
2088. Colonoscopy for Diagnostic Evaluation and Interventions to Prevent Recurrence After Acute Left-Sided Colonic Diverticulitis: A Clinical Guideline From the American College of Physicians.
作者: Amir Qaseem.;Itziar Etxeandia-Ikobaltzeta.;Jennifer S Lin.;Nick Fitterman.;Tatyana Shamliyan.;Timothy J Wilt.; .;Carolyn J Crandall.;Thomas G Cooney.;J Thomas Cross.;Lauri A Hicks.;Michael Maroto.;Reem A Mustafa.;Adam J Obley.;Douglas K Owens.;Jeffrey Tice.;John W Williams.; .
来源: Ann Intern Med. 2022年175卷3期416-431页
The American College of Physicians (ACP) developed this guideline to provide clinical recommendations on the role of colonoscopy for diagnostic evaluation of colorectal cancer (CRC) after a presumed diagnosis of acute left-sided colonic diverticulitis and on the role of pharmacologic, nonpharmacologic, and elective surgical interventions to prevent recurrence after initial treatment of acute complicated and uncomplicated left-sided colonic diverticulitis. This guideline is based on the current best available evidence about benefits and harms, taken in the context of costs and patient values and preferences.
2089. Evaluation and Management After Acute Left-Sided Colonic Diverticulitis : A Systematic Review.
作者: Ethan M Balk.;Gaelen P Adam.;Wangnan Cao.;Shivani Mehta.;Nishit Shah.
来源: Ann Intern Med. 2022年175卷3期388-398页
The value of interventions used after acute colonic diverticulitis is unclear.
2094. Comparative Fracture Risk During Osteoporosis Drug Holidays After Long-Term Risedronate Versus Alendronate Therapy : A Propensity Score-Matched Cohort Study.
作者: Kaleen N Hayes.;Kevin A Brown.;Angela M Cheung.;Sandra A Kim.;David N Juurlink.;Suzanne M Cadarette.
来源: Ann Intern Med. 2022年175卷3期335-343页
An osteoporosis drug holiday is recommended for most patients after 3 to 5 years of therapy. Risedronate has a shorter half-life than alendronate, and thus the residual length of fracture protection may be shorter.
2096. Opioid Use Disorder.
Opioid use disorder (OUD) is a treatable chronic disorder with episodes of remission and recurrence characterized by loss of control of opioid use, compulsive use, and continued use despite harms. If untreated, OUD is associated with significant morbidity and mortality. Buprenorphine and methadone reduce fatal and nonfatal opioid overdose and infectious complications of OUD and are the first-line treatment options. Physicians have an important role to play in diagnosing OUD and its comorbidities, offering evidence-based treatment, and delivering overdose prevention and other harm reduction services to people who continue to use opioids. Interdisciplinary office-based addiction treatment programs support high-quality OUD care.
2097. Prediction of End-Stage Kidney Disease Using Estimated Glomerular Filtration Rate With and Without Race : A Prospective Cohort Study.
作者: Joshua D Bundy.;Katherine T Mills.;Amanda H Anderson.;Wei Yang.;Jing Chen.;Jiang He.; .
来源: Ann Intern Med. 2022年175卷3期305-313页
New estimated glomerular filtration rate (eGFR) equations removed race adjustment, but the impact of its removal on prediction of end-stage kidney disease (ESKD) is unknown.
2100. Residual Confounding in Health Plan Performance Assessments: Evidence From Randomization in Medicaid.
作者: Jacob Wallace.;J Michael McWilliams.;Anthony Lollo.;Janet Eaton.;Chima D Ndumele.
来源: Ann Intern Med. 2022年175卷3期314-324页
Risk adjustment is used widely in payment systems and performance assessments, but the extent to which it distinguishes plan or provider effects from confounding due to patient differences is typically unknown.
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