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1. Examining how resistance training affects bone strength in older adults with rheumatic diseases: a systematic review.
Rheumatic diseases significantly impact global healthcare through disability, lost productivity, and reduced quality of life, making them an important focus for researchers. As physiological changes associated with aging decrease bone mineral density, rheumatic diseases further elevate fracture risk in older adults. Resistance training has been shown to counteract age-related declines through increases in muscle, strength, and bone mineral density, demonstrating its potential for mitigating bone mineral density loss. This systematic review examines the effectiveness of resistance training interventions in maintaining or improving bone mineral density in older adults with rheumatic diseases, an issue of relevance given impaired skeletal integrity linked to these diseases.
2. Unraveling cerebrovascular involvement in EGPA through digital subtraction angiography: case presentation and systematic literature review.
作者: Viren Vasandani.;Sean O'Leary.;Ronak Gandhi.;Elena Diller.;Giri Movva.;John Broussard.;Vijaya Murthy.
来源: BMC Rheumatol. 2025年9卷1期80页
Eosinophilic granulomatosis with polyangiitis (EGPA) involves systemic inflammation of small to medium vessels, with central nervous system (CNS) involvement being rare. While CT (computed tomography) and MRI (magnetic resonance imaging) are standard for diagnosing CNS involvement, digital subtraction angiography (DSA) is infrequently used. We present a unique EGPA case with CNS involvement and review EGPA CNS vascular variations.
3. Clinical Features in VEXAS syndrome: a systematic review.
作者: Adam Al-Hakim.;Scott Goldberg.;Ségolène Gaillard.;Maël Heiblig.;David B Beck.;Sinisa Savic.
来源: Rheumatology (Oxford). 2025年
To systematically characterise the complete phenotypic spectrum of VEXAS (vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic) syndrome through comprehensive analysis of all published cases since its discovery in 2020.
4. Long-term effectiveness of non-surgical interventions for chronic low back pain: a systematic review and meta-analysis.
作者: Hazel J Jenkins.;Leticia Corrêa.;Benjamin T Brown.;Giovanni E Ferreira.;Casper Nim.;Sasha L Aspinall.;Deborah Wareham.;Junghyun Choi.;Christopher G Maher.;Mark J Hancock.
来源: Lancet Rheumatol. 2025年
Chronic low back pain is a long-term recurrent condition. Interventions with sustained benefits are needed to reduce the associated personal and societal burden. We aimed to assess the long-term effectiveness of non-surgical interventions for reducing pain intensity and disability in adults with chronic low back pain.
5. Does osteoarthritis physiotherapy research in South Korea align with the National Institute for Health and Care Excellence guidelines: a systematic review of English and Korean literature.
Osteoarthritis (OA) is a leading cause of lower limb disability worldwide, imposing significant socioeconomic and personal burden. Thus, many internationally recognised organisations have developed management guidelines for this condition. Among these, the National Institute for Health and Care Excellence (NICE) recommends four first-line approaches to osteoarthritis management: education, exercise, self-management, and weight management. Despite the development of guidelines, adherence to OA management recommendations appears to be suboptimal internationally, and little is known about guideline adherence in South Korea. This study aimed to explore whether research-based physiotherapy interventions for OA in South Korea align with the NICE guidelines.
6. Psoriatic arthritis flare incidence, definition and risk factors: a systematic review.
作者: Batoul Hojeij.;Gonul Hazal Koc.;Jolanda Luime.;Marijn Vis.;Laura C Coates.;Marc R Kok.;Ilja Tchetverikov.
来源: Rheumatology (Oxford). 2025年
We systematically reviewed the literature to identify the incidence of psoriatic arthritis (PsA) flare, criteria used to define it, and associated risk factors.
7. Psychosocial factors associated with physical activity, weight management, and sleep in adults with hip and knee osteoarthritis: a systematic review.
作者: Britt van Dongen.;Amber Ronteltap.;Bastiaan Cijs.;Corelien Kloek.;Catherine Bolman.;Rik Crutzen.
来源: BMC Rheumatol. 2025年9卷1期51页
Osteoarthritis (OA) is a chronic disease primarily affecting older adults, mainly impacting the hip and knee joints. The increasing prevalence of OA contributes to rising healthcare demands and costs. Current OA treatment guidelines emphasize the importance of self-management education and guidance, particularly in promoting physical activity and weight management. In addition, improving sleep is crucial for managing OA. Developing effective self-management interventions necessitates a comprehensive understanding of the factors that facilitate these behaviors. Especially for changing health behaviors, it is important to focus on psychosocial factors. Therefore, this systematic review aimed to identify the psychosocial factors associated with physical activity, weight management, and sleep in adults with hip and/or knee OA.
8. Post-traumatic stress disorder and systemic lupus erythematosus: insights from a systematic review.
作者: Konstantinos Parperis.;Maria Papachristodoulou.;Chris Derk.;Savvas Psarelis.;Konstantinos Voskarides.;Andreas Chatzittofis.
来源: Rheumatology (Oxford). 2025年
Emerging evidence suggests that post-traumatic stress disorder (PTSD) may increase susceptibility to autoimmune diseases, including systemic lupus erythematosus (SLE). PTSD-related immune dysregulation is hypothesized to heighten vulnerability to autoimmunity. This systematic review sought to evaluate the relationship between PTSD and the risk of developing SLE, as well as explore potential shared genetic predispositions.
9. Prevalence and factors associated with fatigue in patients with psoriatic arthritis: a systematic review and meta-analysis.
Fatigue is a prominent symptom in patients with psoriatic arthritis (PsA). There was a wide variety of statistics previously reported on fatigue prevalence in patients. This systematic review examined the current literature to derive the overall prevalence of fatigue and risk factors in PsA patients.
10. Intracranial giant cell arteritis: a comprehensive systematic review.
作者: Sagar Patel.;Iva Okaj.;Jessica Scott.;Sukhreet Atwal.;Colin Stark.;Rabia Tahir.;Nader Khalidi.;Mats Junek.
来源: Rheumatology (Oxford). 2025年
Giant cell arteritis (GCA) is increasingly recognized to occur in intracranial vessels with unknown clinical ramifications. We identified all reported cases of intracranial GCA (ICGCA) in the literature to describe common presentations, investigations, treatments, and outcomes.
11. Association between cardiovascular risk factors and the occurrence of giant cell arteritis: a systematic review and meta-analysis.
作者: François Barde.;Lucas Pacoureau.;Alexis Elbaz.;Raphaèle Seror.;Yann Nguyen.
来源: Rheumatology (Oxford). 2025年
We aimed to analyze the association between cardiovascular risks factors and the onset of giant cell arteritis (GCA) through a systematic review and meta-analysis of observational studies.
12. A systematic review and meta-analysis of the response to placebo in clinical trials of inclusion body myositis.
作者: Elie Naddaf.;Michael P Skolka.;Larry Prokop.;Mazen M Dimachkie.;Jean-Yves Hogrel.;Olivier Benveniste.;Zhen Wang.;Jay Mandrekar.;Colin P West.;M Hassan Murad.
来源: Rheumatology (Oxford). 2025年64卷7期4125-4132页
IBM is characterized by slowly progressive muscle weakness making it challenging to detect significant changes in weakness during a clinical trial. Trial participants receiving placebo may behave differently from in natural history studies. We aimed to quantify the change in muscle strength and IBM Functional Rating Scale (IBMFRS) of IBM patients receiving placebo during clinical trials.
13. Treatments for enhancing sleep quality in fibromyalgia: a systematic review and meta-analysis.
作者: Anna Pathak.;Eoin M Kelleher.;Isabelle Brennan.;Raj Amarnani.;Amanda Wall.;Robert Murphy.;Hopin Lee.;Beth Fordham.;Anushka Irani.
来源: Rheumatology (Oxford). 2025年
Sleep disturbance is a key symptom of fibromyalgia and a risk factor for chronic widespread pain. This systematic review and meta-analysis aims to assess the effectiveness of pharmacological treatments and cognitive behavioural therapy (CBT) in improving sleep quality in fibromyalgia patients.
14. The state of data sharing in rheumatology: a systematic review of top journal practices.
作者: Michelle Pham.;Eddy Bagaruka.;Eli Oldham.;Mahad Chaudhry.;Jacob Duncan.;Taylor Gardner.;Annes Elfar.;Eli Paul.;Alicia Ito Ford.;Matt Vassar.
来源: Rheumatology (Oxford). 2025年64卷7期4113-4124页
To evaluate data sharing statement (DSS) inclusion within rheumatology clinical studies published over the past 4 years in 10 top rheumatology journals.
15. Abatacept and the risk of malignancy: a meta-analysis across disease indications.
作者: Benjamin P Zuckerman.;Mark Gibson.;Ritika Roy.;Mark Hughes.;Daksh Mehta.;Zijing Yang.;Maryam Adas.;Kenrick Ng.;Mark D Russell.;Andrew Cope.;Sam Norton.;James Galloway.
来源: Rheumatology (Oxford). 2025年64卷6期3280-3287页
To estimate the association between abatacept use and the incidence of malignancy excluding non-melanomatous skin cancers (NMSCs).
18. Treatment approaches for idiopathic retroperitoneal fibrosis: a systematic review with meta-analysis.
Currently, there is no standard therapy for idiopathic retroperitoneal fibrosis, so a systematic review was undertaken to assess the effectiveness of different treatment approaches.
19. The role of prokinetics in managing gastrointestinal involvement in SSc: a systematic literature review.
作者: Alberto Ezquerra-Durán.;Luis G Alcala-Gonzalez.;Alfredo Guillen-Del-Castillo.;Carmen P Simeón-Aznar.;Elizabeth Barba.;Carolina Malagelada.;Michael Hughes.;Zsuzsanna H McMahan.
来源: Rheumatology (Oxford). 2025年64卷6期3266-3279页
Gastrointestinal involvement (GI) in SSc is frequent and heterogeneous, manifesting with different degrees of dysmotility. This systematic literature review aimed to summarize evidence on prokinetics for treating SSc-related GI dysmotility.
20. Immunobiologics in juvenile dermatomyositis: a systematic review of promising therapeutic advances.
作者: Aline Maria de Oliveira Rocha.;Gabriel Fidelis Ribeiro.;Juliana Capecce Silva.
来源: Reumatologia. 2024年62卷6期447-455页
To identify the most effective treatment for juvenile dermatomyositis (JDM), considering efficacy, safety, impact on patients and improvement in their quality of life.
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