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141. Diagnostic Yield and Synergistic Impact of Needle Aspiration and Forceps Biopsy With Electromagnetic Navigation Bronchoscopy for Peripheral Pulmonary Lesions: A Randomized Controlled Trial.149. A Case of Mediastinal Adenopathy and Clinically Suspected Myocarditis.
作者: Alexandre Terré.;Catherine Julié.;Nathalie Dournon.;Pierre Cappy.;Stephen Binsse.;Thomas Hanslik.;Jean-Emmanuel Kahn.;Camille Montardi.
来源: Chest. 2026年169卷1期e25-e29页
A 29-year-old man originally from an Eastern European country with a high TB incidence had resided in Western Europe for 6 years. He worked in air conditioning repair and currently smoked. He presented to the emergency department with a 10-day history of chest pain, dry cough, and fever. He had no significant medical history, recent travel, animal contact, or insect bites. He denied IV drug use and risk factors for sexually transmitted infections. On admission, his vital signs were stable except for a low-grade fever of 38.5 °C, with no respiratory distress or audible wheezing noted. He was discharged with a diagnosis of a common cold.
151. A 45-Year-Old Woman With Hereditary Hemorrhagic Telangiectasia and Persistent Exertional Dyspnea and Peripheral Edema.
作者: Helen Triantafyllidi.;Dionysia Birmpa.;Anastasia Fambri.;Dimitrios Benas.;David Montani.
来源: Chest. 2026年169卷1期e17-e20页
We report the case of a 45-year-old woman who was referred to our Cardiology Department because of persistent exertional dyspnea and peripheral edema. She had an established clinical diagnosis of hereditary hemorrhagic telangiectasia with multiple gastrointestinal telangiectasias that had been submitted to repeat embolization in the past and arteriovenous malformations in the liver and lungs. Complete blood count was diagnostic for severe anemia (hemoglobin 5-6 g/dL). Since the hereditary hemorrhagic telangiectasia diagnosis 3 years prior, the patient informed us that she has undergone 27 blood transfusions and multiple embolizations to manage gastrointestinal telangiectasias. Given her severe anemia that was caused by gastrointestinal telangiectasia, treatment with bevacizumab was initiated. Bevacizumab was administered over 8 cycles (initially biweekly for 4 doses, followed by monthly administration).
152. A 74-Year-Old Woman With Dyspnea, Muscle Weakness, and Rapidly Progressive Bilateral Diffuse Pulmonary Infiltrates.
作者: Chunli Wu.;Xiaoxiao Zhu.;Qi Dai.;Zhenyue Ye.;Lin Yang.;Yong Zhou.;Zhaoxing Dong.
来源: Chest. 2026年169卷1期e11-e15页
A 74-year-old woman sought treatment with a 4-day history of high fever and rapidly progressive dyspnea. A 2-day course of ceftriaxone and betamethasone administered in an outpatient setting did not result in any clinical improvement, leading to her admission to our hospital. She demonstrated a slight cough but did not report heartburn, night sweats, hemoptysis, myalgia, arthralgia, or weight loss. Her family history was unremarkable.
153. Arterial Stenosis From Sarcoidosis-Associated Adenopathy and Fibrosing Mediastinitis Leading to Pulmonary Infarction.
作者: Matthew Freedman.;Ugochukwu Kingsley Odega.;Allen Ko.;Hannah Mannem.;Catherine A Bonham.
来源: Chest. 2026年169卷1期e1-e4页
Sarcoidosis is a systemic, granulomatous disorder commonly affecting the lungs that has the potential to cause numerous thoracic complications. We present a novel case of a 44-year-old woman with pulmonary sarcoidosis who demonstrated a large pulmonary infarction. The disease presentation ultimately was attributed to arterial stenosis resulting from sarcoidosis-associated fibrosing mediastinitis and compressive mediastinal adenopathy. The patient was treated with an extended course of prednisone and subsequently was transitioned to azathioprine with eventual resolution of symptoms, but persistence of imaging findings. Further treatment strategies were considered, including rituximab and vascular stenting, although not pursued. To our knowledge, this is the first reported case of pulmonary infarction caused by this mechanism, exemplifying the complex ways in which sarcoidosis can manifest.
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