1563. Efficacy of a culturally adapted, cognitive behavioural therapy-based intervention for postnatal depression in British south Asian women (ROSHNI-2): a multicentre, randomised controlled trial.
作者: Nusrat Husain.;Farah Lunat.;Karina Lovell.;Jahanara Miah.;Carolyn A Chew-Graham.;Penny Bee.;Ahmed Waqas.;Matthias Pierce.;Deepali Sharma.;Najia Atif.;Saadia Aseem.;Kamaldeep Bhui.;Peter Bower.;Traolach Brugha.;Nasim Chaudhry.;Akbar Ullah.;Linda Davies.;Nadeem Gire.;Joe Kai.;Jillian Morrison.;Naeem Mohmed.;Shanaya Rathod.;Najma Siddiqi.;Siham Sikander.;Waquas Waheed.;Ilyas Mirza.;Christopher Williams.;Nosheen Zaidi.;Richard Emsley.;Atif Rahman.;Richard Morriss.
来源: Lancet. 2024年404卷10461期1430-1443页
Postnatal depression necessitates timely and effective interventions to mitigate adverse maternal and child outcomes in the short term and over the life course. British south Asian women with depression are often underserved and undertreated due to stigma, language barriers, and cultural barriers. This trial aimed to test the clinical efficacy of a culturally adapted, group cognitive behavioural therapy (CBT)-based intervention, the Positive Health Programme (PHP), delivered by non-specialist health workers for postnatal depression in British south Asian women.
1564. 5-year vaccine protection following a single dose of Vi-tetanus toxoid conjugate vaccine in Bangladeshi children (TyVOID): a cluster randomised trial.
作者: Firdausi Qadri.;Farhana Khanam.;Yiyuan Zhang.;Prasanta Kumar Biswas.;Merryn Voysey.;Yama F Mujadidi.;Sarah Kelly.;Amirul Islam Bhuiyan.;Nazmul Hasan Rajib.;Ismail Hossen.;Nazia Rahman.;Sadia Islam.;Virginia E Pitzer.;Young Chan Kim.;John D Clemens.;Andrew J Pollard.;Xinxue Liu.
来源: Lancet. 2024年404卷10461期1419-1429页
WHO currently recommends a single dose of typhoid conjugate vaccine (TCV) in high-burden countries based on 2-year vaccine efficacy data from large randomised controlled trials. Given the decay of immunogenicity, the protection beyond 2 years is unknown. We therefore extended the follow-up of the TyVAC trial in Bangladesh to assess waning of vaccine protection to 5 years after vaccination.
1565. Reductions in recurrence in women with early breast cancer entering clinical trials between 1990 and 2009: a pooled analysis of 155 746 women in 151 trials.
Distant recurrence in women with oestrogen receptor-positive early breast cancer persists at a constant rate for more than 20 years after diagnosis, with little equivalent data for oestrogen receptor-negative breast cancer. Using the database of the Early Breast Cancer Trialists' Collaborative Group (EBCTCG) we investigated rates of distant breast-cancer recurrence in oestrogen receptor-positive and oestrogen receptor-negative tumours and trends in outcomes over time.
1577. The Lancet Commission on self-harm.
作者: Paul Moran.;Amy Chandler.;Pat Dudgeon.;Olivia J Kirtley.;Duleeka Knipe.;Jane Pirkis.;Mark Sinyor.;Rosie Allister.;Jeffrey Ansloos.;Melanie A Ball.;Lai Fong Chan.;Leilani Darwin.;Kate L Derry.;Keith Hawton.;Veronica Heney.;Sarah Hetrick.;Ang Li.;Daiane B Machado.;Emma McAllister.;David McDaid.;Ishita Mehra.;Thomas Niederkrotenthaler.;Matthew K Nock.;Victoria M O'Keefe.;Maria A Oquendo.;Joseph Osafo.;Vikram Patel.;Soumitra Pathare.;Shanna Peltier.;Tessa Roberts.;Jo Robinson.;Fiona Shand.;Fiona Stirling.;Jon P A Stoor.;Natasha Swingler.;Gustavo Turecki.;Svetha Venkatesh.;Waikaremoana Waitoki.;Michael Wright.;Paul S F Yip.;Michael J Spoelma.;Navneet Kapur.;Rory C O'Connor.;Helen Christensen.
来源: Lancet. 2024年404卷10461期1445-1492页 |