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7995. Cardiac screening with electrocardiography, stress echocardiography, or myocardial perfusion imaging: advice for high-value care from the American College of Physicians.
Cardiac screening in adults with resting or stress electrocardiography, stress echocardiography, or myocardial perfusion imaging can reveal findings associated with increased risk for coronary heart disease events, but inappropriate cardiac testing of low-risk adults has been identified as an important area of overuse by several professional societies.
7996. Cervical spine clearance in obtunded patients after blunt traumatic injury: a systematic review.
作者: Jetan H Badhiwala.;Chung K Lai.;Waleed Alhazzani.;Forough Farrokhyar.;Farshad Nassiri.;Maureen Meade.;Alireza Mansouri.;Niv Sne.;Mohammed Aref.;Naresh Murty.;Christopher Witiw.;Sheila Singh.;Blake Yarascavitch.;Kesava Reddy.;Saleh A Almenawer.
来源: Ann Intern Med. 2015年162卷6期429-37页
Cervical spine clearance protocols are controversial for unconscious patients after blunt traumatic injury and negative findings on computed tomography (CT).
7997. Effect of a culture-based screening algorithm on tuberculosis incidence in immigrants and refugees bound for the United States: a population-based cross-sectional study.
Before 2007, immigrants and refugees bound for the United States were screened for tuberculosis (TB) by a smear-based algorithm that could not diagnose smear-negative/culture-positive TB. In 2007, the Centers for Disease Control and Prevention implemented a culture-based algorithm.
7998. Cost-effectiveness of novel regimens for the treatment of hepatitis C virus.
作者: Mehdi Najafzadeh.;Karin Andersson.;William H Shrank.;Alexis A Krumme.;Olga S Matlin.;Troyen Brennan.;Jerry Avorn.;Niteesh K Choudhry.
来源: Ann Intern Med. 2015年162卷6期407-19页
New regimens for hepatitis C virus (HCV) have shorter treatment durations and increased rates of sustained virologic response compared with existing therapies but are extremely expensive.
7999. Cost-effectiveness and budget impact of hepatitis C virus treatment with sofosbuvir and ledipasvir in the United States.
作者: Jagpreet Chhatwal.;Fasiha Kanwal.;Mark S Roberts.;Michael A Dunn.
来源: Ann Intern Med. 2015年162卷6期397-406页
Sofosbuvir and ledipasvir, which have recently been approved for treatment of chronic hepatitis C virus (HCV) infection, are more efficacious and safer than the old standard of care (oSOC) but are substantially more expensive. Whether and in which patients their improved efficacy justifies their increased cost is unclear.
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