75. Conservative Oxygen Therapy in Mechanically Ventilated Critically Ill Adult Patients: The UK-ROX Randomized Clinical Trial.
作者: Daniel S Martin.;Doug W Gould.;Tasnin Shahid.;James C Doidge.;Alex Cowden.;Zia Sadique.;Julie Camsooksai.;Walton N Charles.;Miriam Davey.;Amelia Francis-Johnson.;Roger M Garrett.;Michael P W Grocott.;Joanne Jones.;Lamprini Lampro.;Diane M Mackle.;B Ronan O'Driscoll.;Alvin Richards-Belle.;Anthony J Rostron.;Tamás Szakmány.;Alex Warren.;Paul J Young.;Kathryn M Rowan.;David A Harrison.;Paul R Mouncey.; .
来源: JAMA. 2025年
Supplemental oxygen is frequently given to patients in intensive care units (ICUs); however, there is insufficient evidence to guide its therapeutic use and to minimize the potential harm caused by administering too little or too much.
79. Augmented Enteral Protein During Critical Illness: The TARGET Protein Randomized Clinical Trial.
作者: Matthew J Summers.;Lee-Anne S Chapple.;Amalia Karahalios.;Rinaldo Bellomo.;Marianne J Chapman.;Suzie Ferrie.;Mark E Finnis.;Craig French.;Sally Hurford.;Nima Kakho.;Matthew J Maiden.;Stephanie N O'Connor.;Sandra L Peake.;Jeffrey J Presneill.;Emma J Ridley.;An Tran-Duy.;Patricia J Williams.;Paul J Young.;Sophie Zaloumis.;Adam M Deane.; .
来源: JAMA. 2025年
Guidelines recommend augmenting enteral protein during critical illness, but the impact on patient outcomes is uncertain.
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