7661. Cost-effectiveness of novel regimens for the treatment of hepatitis C virus.
作者: Mehdi Najafzadeh.;Karin Andersson.;William H Shrank.;Alexis A Krumme.;Olga S Matlin.;Troyen Brennan.;Jerry Avorn.;Niteesh K Choudhry.
来源: Ann Intern Med. 2015年162卷6期407-19页
New regimens for hepatitis C virus (HCV) have shorter treatment durations and increased rates of sustained virologic response compared with existing therapies but are extremely expensive.
7662. Cost-effectiveness and budget impact of hepatitis C virus treatment with sofosbuvir and ledipasvir in the United States.
作者: Jagpreet Chhatwal.;Fasiha Kanwal.;Mark S Roberts.;Michael A Dunn.
来源: Ann Intern Med. 2015年162卷6期397-406页
Sofosbuvir and ledipasvir, which have recently been approved for treatment of chronic hepatitis C virus (HCV) infection, are more efficacious and safer than the old standard of care (oSOC) but are substantially more expensive. Whether and in which patients their improved efficacy justifies their increased cost is unclear.
7665. Validation of the appropriate use criteria for coronary angiography: a cohort study.
作者: Michael M Mohareb.;Feng Qiu.;Warren J Cantor.;Kori J Kingsbury.;Dennis T Ko.;Harindra C Wijeysundera.
来源: Ann Intern Med. 2015年162卷8期549-56页
The use of invasive coronary angiography in stable ischemic heart disease (IHD) varies widely.
7666. In the clinic. Type 2 diabetes.
This issue provides a clinical overview of Type 2 Diabetes focusing on prevention, diagnosis, treatment, practice improvement, and patient information. The content of In the Clinic is drawn from the clinical information and education resources of the American College of Physicians (ACP), including ACP Smart Medicine and MKSAP (Medical Knowledge and Self-Assessment Program). Annals of Internal Medicine editors develop In the Clinic from these primary sources in collaboration with the ACP's Medical Education and Publishing divisions and with the assistance of science writers and physician writers. Editorial consultants from ACP Smart Medicine and MKSAP provide expert review of the content. Readers who are interested in these primary resources for more detail can consult http://smartmedicine.acponline.org, http://mksap.acponline.org, and other resources referenced in each issue of In the Clinic.
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