7292. Long-Term Pioglitazone Treatment for Patients With Nonalcoholic Steatohepatitis and Prediabetes or Type 2 Diabetes Mellitus: A Randomized Trial.
作者: Kenneth Cusi.;Beverly Orsak.;Fernando Bril.;Romina Lomonaco.;Joan Hecht.;Carolina Ortiz-Lopez.;Fermin Tio.;Jean Hardies.;Celia Darland.;Nicolas Musi.;Amy Webb.;Paola Portillo-Sanchez.
来源: Ann Intern Med. 2016年165卷5期305-15页
The metabolic defects of nonalcoholic steatohepatitis (NASH) and prediabetes or type 2 diabetes mellitus (T2DM) seem to be specifically targeted by pioglitazone. However, information about its long-term use in this population is limited.
7294. Hepatitis C Core Antigen Testing for Diagnosis of Hepatitis C Virus Infection: A Systematic Review and Meta-analysis.
作者: J Morgan Freiman.;Trang M Tran.;Samuel G Schumacher.;Laura F White.;Stefano Ongarello.;Jennifer Cohn.;Philippa J Easterbrook.;Benjamin P Linas.;Claudia M Denkinger.
来源: Ann Intern Med. 2016年165卷5期345-55页
Diagnosis of chronic hepatitis C virus (HCV) infection requires both a positive HCV antibody screen and confirmatory nucleic acid testing (NAT). Testing for hepatitis C virus core antigen (HCVcAg) is a potential alternative to NAT.
7295. Comparing Use of Low-Value Health Care Services Among U.S. Advanced Practice Clinicians and Physicians.
作者: John N Mafi.;Christina C Wee.;Roger B Davis.;Bruce E Landon.
来源: Ann Intern Med. 2016年165卷4期237-44页
Many physicians believe that advanced practice clinicians (APCs [nurse practitioners and physician assistants]) provide care of relatively lower value.
7296. The Prevalence of Resident-to-Resident Elder Mistreatment in Nursing Homes.
作者: Mark S Lachs.;Jeanne A Teresi.;Mildred Ramirez.;Kimberly van Haitsma.;Stephanie Silver.;Joseph P Eimicke.;Gabriel Boratgis.;Gail Sukha.;Jian Kong.;Alexandra M Besas.;Maria Reyes Luna.;Karl A Pillemer.
来源: Ann Intern Med. 2016年165卷4期229-36页
Resident-to-resident elder mistreatment (R-REM) in nursing homes can cause physical and psychological injury and death, yet its prevalence remains unknown.
7297. Cardiovascular Events Associated With Use of Tyrosine Kinase Inhibitors in Chronic Myeloid Leukemia: A Population-Based Cohort Study.
作者: Torsten Dahlén.;Gustaf Edgren.;Mats Lambe.;Martin Höglund.;Magnus Björkholm.;Fredrik Sandin.;Anders Själander.;Johan Richter.;Ulla Olsson-Strömberg.;Lotta Ohm.;Magnus Bäck.;Leif Stenke.; .
来源: Ann Intern Med. 2016年165卷3期161-6页
Tyrosine kinase inhibitors (TKIs) have increased survival dramatically for patients with chronic myeloid leukemia (CML), but continuous administration of these drugs may elicit long-term toxicity.
7299. ClinicalTrials.gov and Drugs@FDA: A Comparison of Results Reporting for New Drug Approval Trials.
作者: Lisa M Schwartz.;Steven Woloshin.;Eugene Zheng.;Tony Tse.;Deborah A Zarin.
来源: Ann Intern Med. 2016年165卷6期421-30页
Pharmaceutical companies and other trial sponsors must submit certain trial results to ClinicalTrials.gov. The validity of these results is unclear.
|