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6941. Epilepsy.
This issue provides a clinical overview of epilepsy, focusing on diagnosis, prevention, treatment, and further considerations. The content of In the Clinic is drawn from the clinical information and education resources of the American College of Physicians (ACP), including MKSAP (Medical Knowledge and Self-Assessment Program). Annals of Internal Medicine editors develop In the Clinic in collaboration with the ACP's Medical Education and Publishing divisions and with the assistance of additional science writers and physician writers.
6947. Should Patients Have Periodic Health Examinations?: Grand Rounds Discussion From Beth Israel Deaconess Medical Center.
作者: Eileen E Reynolds.;James Heffernan.;Ateev Mehrotra.;Howard Libman.
来源: Ann Intern Med. 2016年164卷3期176-83页
Physicians and patients have come to expect that periodic health examinations (PHEs) are a standard part of comprehensive ongoing medical care. However, considerable research has not demonstrated a substantial benefit of the PHE. Given this lack of benefit and the high total cost of PHE to the health care system, the American Board of Internal Medicine (ABIM) Foundation and the Society of General Internal Medicine (SGIM) have identified "routine health checks in asymptomatic patients" as something of low value that physicians and patients should question, as a part of the Choosing Wisely campaign. Two discussants review the debate about PHE and consider the value of PHE for a healthy 70-year-old woman who appreciates seeing her physician annually.
6950. Fecal Immunochemical Test Program Performance Over 4 Rounds of Annual Screening: A Retrospective Cohort Study.
作者: Christopher D Jensen.;Douglas A Corley.;Virginia P Quinn.;Chyke A Doubeni.;Ann G Zauber.;Jeffrey K Lee.;Wei K Zhao.;Amy R Marks.;Joanne E Schottinger.;Nirupa R Ghai.;Alexander T Lee.;Richard Contreras.;Carrie N Klabunde.;Charles P Quesenberry.;Theodore R Levin.;Pauline A Mysliwiec.
来源: Ann Intern Med. 2016年164卷7期456-63页
The fecal immunochemical test (FIT) is a common method for colorectal cancer (CRC) screening, yet its acceptability and performance over several rounds of annual testing are largely unknown.
6952. Hematuria as a Marker of Occult Urinary Tract Cancer: Advice for High-Value Care From the American College of Physicians.
The presence of blood in the urine, or hematuria, is a common finding in clinical practice and can sometimes be a sign of occult cancer. This article describes the clinical epidemiology of hematuria and the current state of practice and science in this context and provides suggestions for clinicians evaluating patients with hematuria.
6954. Disclosing Pleiotropic Effects During Genetic Risk Assessment for Alzheimer Disease: A Randomized Trial.
作者: Kurt D Christensen.;J Scott Roberts.;Peter J Whitehouse.;Charmaine D M Royal.;Thomas O Obisesan.;L Adrienne Cupples.;Jacqueline A Vernarelli.;Deepak L Bhatt.;Erin Linnenbringer.;Melissa B Butson.;Grace-Ann Fasaye.;Wendy R Uhlmann.;Susan Hiraki.;Na Wang.;Robert Cook-Deegan.;Robert C Green.; .
来源: Ann Intern Med. 2016年164卷3期155-63页
Increasing use of genetic testing raises questions about disclosing secondary findings, including pleiotropic information.
6956. Sharing Clinical Trial Data: A Proposal From the International Committee of Medical Journal Editors.
作者: Darren B Taichman.;Joyce Backus.;Christopher Baethge.;Howard Bauchner.;Peter W de Leeuw.;Jeffrey M Drazen.;John Fletcher.;Frank A Frizelle.;Trish Groves.;Abraham Haileamlak.;Astrid James.;Christine Laine.;Larry Peiperl.;Anja Pinborg.;Peush Sahni.;Sinan Wu.
来源: Ann Intern Med. 2016年164卷7期505-6页 6957. Appropriate Antibiotic Use for Acute Respiratory Tract Infection in Adults: Advice for High-Value Care From the American College of Physicians and the Centers for Disease Control and Prevention.
Acute respiratory tract infection (ARTI) is the most common reason for antibiotic prescription in adults. Antibiotics are often inappropriately prescribed for patients with ARTI. This article presents best practices for antibiotic use in healthy adults (those without chronic lung disease or immunocompromising conditions) presenting with ARTI.
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