6234. Novel Stool-Based Protein Biomarkers for Improved Colorectal Cancer Screening: A Case-Control Study.
作者: Linda J W Bosch.;Meike de Wit.;Thang V Pham.;Veerle M H Coupé.;Annemieke C Hiemstra.;Sander R Piersma.;Gideon Oudgenoeg.;George L Scheffer.;Sandra Mongera.;Jochim Terhaar Sive Droste.;Frank A Oort.;Sietze T van Turenhout.;Ilhame Ben Larbi.;Joost Louwagie.;Wim van Criekinge.;Rene W M van der Hulst.;Chris J J Mulder.;Beatriz Carvalho.;Remond J A Fijneman.;Connie R Jimenez.;Gerrit A Meijer.
来源: Ann Intern Med. 2017年167卷12期855-866页
The fecal immunochemical test (FIT) for detecting hemoglobin is used widely for noninvasive colorectal cancer (CRC) screening, but its sensitivity leaves room for improvement.
6236. What Recent History Has Taught Us About Responding to Emerging Infectious Disease Threats.
作者: Catharine I Paules.;Robert W Eisinger.;Hilary D Marston.;Anthony S Fauci.
来源: Ann Intern Med. 2017年167卷11期805-811页
Presidential administrations face any number of unexpected crises during their tenure, and global pandemics are among the most challenging. As of January 2017, one of the authors had served under 5 presidents as the director of the National Institute of Allergy and Infectious Diseases at the National Institutes of Health. During each administration, the government faced unexpected pandemics, ranging from the HIV/AIDS pandemic, which began during the Reagan administration, to the recent Zika outbreak in the Americas, which started during the Obama administration. These experiences underscored the need to optimize preparation for and response to these threats whenever and wherever they emerge. This article recounts selected outbreaks occurring during this period and highlights lessons that were learned that can be applied to the infectious disease threats that will inevitably be faced in the current presidential administration and beyond.
6239. Aspirin in Patients With Previous Percutaneous Coronary Intervention Undergoing Noncardiac Surgery.
作者: Michelle M Graham.;Daniel I Sessler.;Joel L Parlow.;Bruce M Biccard.;Gordon Guyatt.;Kate Leslie.;Matthew T V Chan.;Christian S Meyhoff.;Denis Xavier.;Alben Sigamani.;Priya A Kumar.;Marko Mrkobrada.;Deborah J Cook.;Vikas Tandon.;Jesus Alvarez-Garcia.;Juan Carlos Villar.;Thomas W Painter.;Giovanni Landoni.;Edith Fleischmann.;Andre Lamy.;Richard Whitlock.;Yannick Le Manach.;Meylin Aphang-Lam.;Juan P Cata.;Peggy Gao.;Nicolaas C S Terblanche.;Pamidimukkala V Ramana.;Kim A Jamieson.;Amal Bessissow.;Gabriela R Mendoza.;Silvia Ramirez.;Pierre A Diemunsch.;Salim Yusuf.;P J Devereaux.
来源: Ann Intern Med. 2018年168卷4期237-244页
Uncertainty remains about the effects of aspirin in patients with prior percutaneous coronary intervention (PCI) having noncardiac surgery.
|