342. Oral Nalbuphine in Idiopathic Pulmonary Fibrosis-Associated Cough: The CORAL Randomized Clinical Trial.
作者: Philip L Molyneaux.;Nesrin Mogulkoc.;Hakan Gunen.;Anna Doboszynska.;Michael Kreuter.;Blue Neustifter.;Vandana Mathur.;James Cassella.; .
来源: JAMA. 2026年335卷12期1050-1059页
For patients with idiopathic pulmonary fibrosis (IPF), cough impairs quality of life; effective treatments for IPF-associated cough are needed.
343. Restless Legs Syndrome: A Review.
Restless legs syndrome (RLS) is a sleep-related movement disorder that affects approximately 3% of US adults to a clinically significant extent and can cause substantial sleep disturbance.
345. Antibiotic Therapy for Uncomplicated Acute Appendicitis: Ten-Year Follow-Up of the APPAC Randomized Clinical Trial.
作者: Paulina Salminen.;Roosa Salminen.;Johanna Kallio.;Saija Hurme.;Pia Nordström.;Tuomo Rantanen.;Hannu Paajanen.;Markku Aarnio.;Jukka-Pekka Mecklin.;Juhani Sand.;Juha M Grönroos.;Tero Rautio.
来源: JAMA. 2026年335卷12期1041-1049页
Antibiotic therapy is effective and safe for uncomplicated acute appendicitis in adults, but randomized clinical trial results exceeding 5 years are missing.
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