261. Extended Caffeine for Apnea in Moderately Preterm Infants: The MoCHA Randomized Clinical Trial.
作者: Waldemar A Carlo.;Eric C Eichenwald.;Benjamin A Carper.;Edward F Bell.;Martin Keszler.;Ravi M Patel.;Pablo J Sánchez.;Ronald N Goldberg.;Carl T D'Angio.;Krisa P Van Meurs.;Anna Maria Hibbs.;Namasivayam Ambalavanan.;Shirley S Cosby.;Nancy S Newman.;Betty R Vohr.;Michele C Walsh.;Abhik Das.;Robin K Ohls.;Janell Fuller.;Matthew A Rysavy.;Sarvin Ghavam.;Luc P Brion.;Karen M Puopolo.;Ryan Moore.;Michelle L Baack.;Tarah T Colaizy.;Mariana Baserga.;Ahmed F Osman.;Stephanie L Merhar.;Brenda B Poindexter.;Sara B DeMauro.;Vasanth Kumar.;C Michael Cotten.; .
来源: JAMA. 2025年333卷24期2154-2163页
Hospitalization of moderately preterm infants may be prolonged while waiting for apnea of prematurity to resolve after discontinuing caffeine.
266. Long-Term Spending of Accountable Care Organizations in the Medicare Shared Savings Program.
作者: Amelia M Bond.;Yasin Civelek.;William L Schpero.;Lawrence P Casalino.;Manyao Zhang.;Reekarl Pierre.;Dhruv Khullar.
来源: JAMA. 2025年333卷21期1897-1905页
Evidence from initial cohorts of accountable care organizations (ACOs) participating in the Medicare Shared Savings Program (MSSP) found modest reductions in health care spending. Little is known about whether these effects have changed over time.
267. Non-Cystic Fibrosis Bronchiectasis in Adults: A Review.
Non-cystic fibrosis (CF) bronchiectasis is a chronic lung condition caused by permanent bronchial dilatation and inflammation and is characterized by daily cough, sputum, and recurrent exacerbations. Approximately 500 000 people in the US have non-CF bronchiectasis.
280. Metformin for Knee Osteoarthritis in Patients With Overweight or Obesity: A Randomized Clinical Trial.
作者: Feng Pan.;Yuanyuan Wang.;Yuan Z Lim.;Donna M Urquhart.;Mahnuma Mahfuz Estee.;Anita E Wluka.;Rory Wolfe.;Flavia M Cicuttini.
来源: JAMA. 2025年333卷20期1804-1812页
Preclinical and preliminary human evidence suggests that metformin, a first-line treatment for type 2 diabetes, reduces inflammation, preserves cartilage, and improves knee pain in knee osteoarthritis.
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