204. The Microbiome and Cancer: A Translational Science Review.
Growing evidence suggests that microbes located within the gastrointestinal tract and other anatomical locations influence the development and progression of diseases such as cancer.
207. Antihypertensive Medication Timing and Cardiovascular Events and Death: The BedMed Randomized Clinical Trial.
作者: Scott R Garrison.;Jeffrey A Bakal.;Michael R Kolber.;Christina S Korownyk.;Lee A Green.;Jessica E M Kirkwood.;Finlay A McAlister.;Raj S Padwal.;Richard Lewanczuk.;Michael D Hill.;Alexander G Singer.;Alan Katz.;Michael D Kelmer.;Armine Gayayan.;Farah N Campbell.;Ana Vucenovic.;Nathan R Archibald.;Jack M S Yeung.;Erik R E Youngson.;Kimberlyn McGrail.;Braden G O'Neill.;Michelle Greiver.;Donna P Manca.;Roni Y Kraut.;Ting Wang.;Braden J Manns.;Dee A Mangin.;Cathy MacLean.;James McCormack.;Sabrina T Wong.;Colleen Norris.;G Michael Allan.
来源: JAMA. 2025年333卷23期2061-2072页
Whether administration of blood pressure medications at bedtime instead of in the morning reduces cardiovascular risk is unknown, as findings from large clinical trials have not been consistent. There is also concern that bedtime antihypertensive use could induce glaucoma-related visual loss or other hypotensive/ischemic adverse effects.
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