219. Treatment for Brain Metastases With Stereotactic Radiation vs Hippocampal-Avoidance Whole Brain Radiation: A Randomized Clinical Trial.
作者: Ayal A Aizer.;Kee-Young Shin.;Paul J Catalano.;Ivy Ricca.;Marciana Johnson.;Grant Benham.;Kristin Roper.;Beverly Spicer.;Eileen Mann.;Jennifer Nosker.;Michael W Parsons.;Mallika L Mendu.;Jaroslaw Hepel.;Fallon Chipidza.;Monica Krishnan.;Diana D Shi.;Nayan Lamba.;Itai Pashtan.;Luke Peng.;Brian Alexander.;Paul D Brown.;Patrick Y Wen.;Daphne A Haas-Kogan.;Rifaquat Rahman.;Shyam Tanguturi.
来源: JAMA. 2026年335卷13期1127-1136页
Brain metastases are common in patients with cancer, and radiation is often used for management. Among patients with more than 4 brain metastases, the effects of stereotactic radiation targeting only individual tumors, compared with whole brain radiation with hippocampal avoidance, which radiates both tumors and normal brain, remain unknown.
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