2138. LANDMARK comparison of early outcomes of newer-generation Myval transcatheter heart valve series with contemporary valves (Sapien and Evolut) in real-world individuals with severe symptomatic native aortic stenosis: a randomised non-inferiority trial.
作者: Andreas Baumbach.;Niels van Royen.;Ignacio J Amat-Santos.;Martin Hudec.;Matjaz Bunc.;Alexander Ijsselmuiden.;Peep Laanmets.;Daniel Unic.;Bela Merkely.;Renicus S Hermanides.;Vlasis Ninios.;Marcin Protasiewicz.;Benno J W M Rensing.;Pedro L Martin.;Fausto Feres.;Manuel De Sousa Almeida.;Eric van Belle.;Axel Linke.;Alfonso Ielasi.;Matteo Montorfano.;Mark Webster.;Konstantinos Toutouzas.;Emmanuel Teiger.;Francesco Bedogni.;Michiel Voskuil.;Manuel Pan.;Oskar Angerås.;Won-Keun Kim.;Jürgen Rothe.;Ivica Kristić.;Vicente Peral.;Scot Garg.;Hesham Elzomor.;Akihiro Tobe.;Marie-Claude Morice.;Yoshinobu Onuma.;Osama Soliman.;Patrick W Serruys.; .
来源: Lancet. 2024年403卷10445期2695-2708页
Transcatheter aortic valve implantation is an established, guideline-endorsed treatment for severe aortic stenosis. Precise sizing of the balloon-expandable Myval transcatheter heart valve (THV) series with the aortic annulus is facilitated by increasing its diameter in 1·5 mm increments, compared with the usual 3 mm increments in valve size. The LANDMARK trial aimed to show non-inferiority of the Myval THV series compared with the contemporary THVs Sapien Series (Edwards Lifesciences, Irvine, CA, USA) or Evolut Series (Medtronic, Minneapolis, MN, USA).
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