1. Sex Differences in Utilization of Donation After Circulatory Death Donors for Heart Transplantation and Associated Outcomes.
作者: Ersilia M DeFilippis.;Maria Masotti.;Elena M Donald.;Joanna Eichler.;Bhavadharini Ramu.;Tessa Watt.;Michael S Mulvihill.;Koji Takeda.;Nir Uriel.;Rebecca Cogswell.
来源: Circ Heart Fail. 2025年e012835页
The use of donation after circulatory death (DCD) donors for heart transplantation (HT) is increasing in the United States. Whether sex differences exist in DCD HT utilization and outcomes is unknown.
3. Improving Clinical Utility of Fetal Cine CMR Using Deep Learning Super-Resolution.
作者: Thomas M Vollbrecht.;Christopher Hart.;Christoph Katemann.;Alexander Isaak.;Marilia B Voigt.;Claus C Pieper.;Daniel Kuetting.;Annegret Geipel.;Brigitte Strizek.;Julian A Luetkens.
来源: Circ Cardiovasc Imaging. 2025年e018090页
Fetal cardiovascular magnetic resonance is an emerging tool for prenatal congenital heart disease assessment, but long acquisition times and fetal movements limit its clinical use. This study evaluates the clinical utility of deep learning super-resolution reconstructions for rapidly acquired, low-resolution fetal cardiovascular magnetic resonance.
5. Diagnostic Validity of Acetylcholine Provocation Protocols in the Evaluation of Coronary Artery Spasm in Patients With ANOCA.
作者: Rajan Rehan.;Chinmay Khandur.;Christopher C Y Wong.;James Weaver.;Pankaj Jain.;Mark Adams.;Martin K C Ng.;Jennifer A Tremmel.;Andy S C Yong.
来源: Circ Cardiovasc Interv. 2025年e015339页
Coronary artery spasm (CAS) is a common cause of angina with nonobstructive coronary arteries (ANOCA). While acetylcholine provocation testing is the diagnostic gold standard, protocol variations have led to discrepancies in diagnostic accuracy. This study aimed to compare the diagnostic validity of conventional versus high-dose acetylcholine regimens in patients with ANOCA.
6. Invasive Coronary Function Testing in Patients With Prior PCI Who Have Persistent ANOCA.
作者: Vedant S Pargaonkar.;Christopher C Y Wong.;Yasuhiro Honda.;Ingela Schnittger.;Jennifer A Tremmel.
来源: Circ Cardiovasc Interv. 2025年e015344页
Patients with postpercutaneous coronary intervention (PCI) angina are challenging to manage. Comprehensive coronary function testing (CFT) can identify occult coronary abnormalities in patients with angina and nonobstructive coronary arteries. Its utility in patients with post-PCI and persistent angina who have no obstructive coronary artery disease is unexplored.
7. Letter by Sacoransky Regarding Article, "Deep Learning-Derived Cardiac Chamber Volumes and Mass From PET/CT Attenuation Scans: Associations With Myocardial Flow Reserve and Heart Failure".8. Race Comparisons in Patients With Cardiac Sarcoidosis: Insights From the Cardiac Sarcoidosis Consortium.
作者: Angkawipa Trongtorsak.;Junior De La Rosa Martinez.;Thomas C Crawford.;Frank M Bogun.;Xiaokui Gu.;Eric Purroll.;Kenneth A Ellenbogen.;Alexandru B Chicos.;Henri Roukoz.;Peter J Zimetbaum.;Steven J Kalbfleisch.;Francis D Murgatroyd.;David A Steckman.;Lynda E Rosenfeld.;Kyoko Soejima.;Adarsh K Bhan.;Vasanth Vedantham.;Timm-Michael L Dickfeld.;David B De Lurgio.;Pyotr G Platonov.;Matthew M Zipse.;Suguru Nishiuchi.;Matthew L Ortman.;Calambur Narasimhan.;Kristen K Patton.;David G Rosenthal.;Siddharth S Mukerji.;Jarieke C Hoogendoorn.;Katja Zeppenfeld.;Mikhail Torosoff.;Marc A Judson.;Katherine Martin.;Christopher Madias.;Melody Hermel.;Khaled Nour.;Estelle Torbey.;William H Sauer.;Jordana Kron.; .
来源: Circ Arrhythm Electrophysiol. 2025年e013670页
Differences in cardiac sarcoidosis between racial groups remain understudied. Therefore, this study aims to explore race differences in patients with cardiac sarcoidosis.
9. Early Atrial Remodeling Drives Arrhythmia in Fabry Disease.
作者: Ashwin Roy.;Christopher O'Shea.;Albert Dasí.;Leena Patel.;Max J Cumberland.;Daniel Nieves.;Hansel Canagarajah.;Sophie Thompson.;Amar Azad.;Anna Price.;Caitlin Hall.;Amor Mia Alvior.;Phalguni Rath.;Ben Davies.;Blanca Rodriguez.;Andrew P Holmes.;Davor Pavlovic.;Jonathan N Townend.;Tarekegn Geberhiwot.;Katja Gehmlich.;Richard P Steeds.
来源: Circ Arrhythm Electrophysiol. 2025年e013352页
Fabry disease (FD) is an X-linked lysosomal storage disorder caused by α-Gal A (α-galactosidase A) deficiency, resulting in multiorgan accumulation of sphingolipid, namely globotriaosylceramide. This triggers ventricular myocardial hypertrophy, fibrosis, and inflammation, driving arrhythmia and sudden death. Atrial fibrillation is common, yet the cellular mechanisms accounting for this are unknown.
10. Wearable Irregular Heart Rhythm Detection Recurrences and Electrocardiographic Atrial Fibrillation Confirmation: The Fitbit Heart Study.
作者: Steven A Lubitz.;Michael V McConnell.;Caitlin Selvaggi.;Aparna Krishnamoorthy.;Steven J Atlas.;David D McManus.;Sherry Pagoto.;Daniel E Singer.;Alexandros Pantelopoulos.;Andrea S Foulkes.;Anthony Z Faranesh.
来源: Circ Arrhythm Electrophysiol. 2025年e013565页
Wrist-worn wearables can detect irregular heart rhythms using photoplethysmography, but ECGs are required to confirm atrial fibrillation (AF). We sought to determine the frequency of a recurrent irregular heart rhythm detection (IHRD; ≥30 minutes of an irregular rhythm), estimate the potential diagnostic yield of different electrocardiographic monitoring strategies for confirming AF, and identify predictors of recurrent IHRDs.
12. Mitochondrial 1-Carbon Metabolism Drives CD34-Lineage Cells to Differentiate Into T Follicular Helper Cells to Form Tertiary Lymphoid Organs in Transplant Arteriosclerosis.
作者: Xuejing Sun.;Junru Wu.;Tian He.;Meng Yao.;Li Qin.;Chunyan Weng.;Liping Peng.;Qingzhong Xiao.;Yao Lu.;Hong Yuan.;Qingbo Xu.;Jingjing Cai.
来源: Circulation. 2025年
Allograft arteriosclerosis, a significant cause of graft failure, is linked to the formation of tertiary lymphoid organs. T follicular helper (Tfh) cells are a vital subset of helper T cells that control the formation of the germinal center in tertiary lymphoid organs. Thus, understanding the origins and regulatory mechanisms of Tfh cells in allograft arteriosclerosis is essential for developing targeted therapies.
13. Correction to: Toward Heart-Healthy and Sustainable Cities: A Policy Statement From the American Heart Association.
作者: Sanjay Rajagopalan.;Anu Ramaswami.;Aruni Bhatnagar.;Robert D Brook.;Mark Fenton.;Christopher Gardner.;Roni Neff.;Armistead G Russell.;Karen C Seto.;Laurie P Whitsel.; .
来源: Circulation. 2025年151卷25期e1097页 14. Correction to: 2025 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association.
作者: Seth S Martin.;Aaron W Aday.;Norrina B Allen.;Zaid I Almarzooq.;Cheryl A M Anderson.;Pankaj Arora.;Christy L Avery.;Carissa M Baker-Smith.;Nisha Bansal.;Andrea Z Beaton.;Yvonne Commodore-Mensah.;Maria E Currie.;Mitchell S V Elkind.;Wenjun Fan.;Giuliano Generoso.;Bethany Barone Gibbs.;Debra G Heard.;Swapnil Hiremath.;Michelle C Johansen.;Dhruv S Kazi.;Darae Ko.;Michelle H Leppert.;Jared W Magnani.;Erin D Michos.;Michael E Mussolino.;Nisha I Parikh.;Sarah M Perman.;Mary Rezk-Hanna.;Gregory A Roth.;Nilay S Shah.;Mellanie V Springer.;Marie-Pierre St-Onge.;Evan L Thacker.;Sarah M Urbut.;Harriette G C Van Spall.;Jenifer H Voeks.;Seamus P Whelton.;Nathan D Wong.;Sally S Wong.;Kristine Yaffe.;Latha P Palaniappan.; .
来源: Circulation. 2025年151卷25期e1096页 15. Correction to: 2025 ACC/AHA/ACEP/NAEMSP/SCAI Guideline for the Management of Patients With Acute Coronary Syndromes: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.
作者: Sunil V Rao.;Michelle L O'Donoghue.;Marc Ruel.;Tanveer Rab.;Jaqueline E Tamis-Holland.;John H Alexander.;Usman Baber.;Heather Baker.;Mauricio G Cohen.;Mercedes Cruz-Ruiz.;Leslie L Davis.;James A de Lemos.;Tracy A DeWald.;Islam Y Elgendy.;Dmitriy N Feldman.;Abhinav Goyal.;Ijeoma Isiadinso.;Venu Menon.;David A Morrow.;Debabrata Mukherjee.;Elke Platz.;Susan B Promes.;Sigrid Sandner.;Yader Sandoval.;Rachel Schunder.;Binita Shah.;Jason P Stopyra.;Amy W Talbot.;Pam R Taub.;Marlene S Williams.
来源: Circulation. 2025年151卷25期e1098页 16. Correction to: 2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association.
作者: Seth S Martin.;Aaron W Aday.;Zaid I Almarzooq.;Cheryl A M Anderson.;Pankaj Arora.;Christy L Avery.;Carissa M Baker-Smith.;Bethany Barone Gibbs.;Andrea Z Beaton.;Amelia K Boehme.;Yvonne Commodore-Mensah.;Maria E Currie.;Mitchell S V Elkind.;Kelly R Evenson.;Giuliano Generoso.;Debra G Heard.;Swapnil Hiremath.;Michelle C Johansen.;Rizwan Kalani.;Dhruv S Kazi.;Darae Ko.;Junxiu Liu.;Jared W Magnani.;Erin D Michos.;Michael E Mussolino.;Sankar D Navaneethan.;Nisha I Parikh.;Sarah M Perman.;Remy Poudel.;Mary Rezk-Hanna.;Gregory A Roth.;Nilay S Shah.;Marie-Pierre St-Onge.;Evan L Thacker.;Connie W Tsao.;Sarah M Urbut.;Harriette G C Van Spall.;Jenifer H Voeks.;Nae-Yuh Wang.;Nathan D Wong.;Sally S Wong.;Kristine Yaffe.;Latha P Palaniappan.; .
来源: Circulation. 2025年151卷25期e1095页 17. Response by Duan and Lin to Letter Regarding Article, "Bone Morphogenetic Protein 9 Protects Against Myocardial Infarction by Improving Lymphatic Drainage Function and Triggering DECR1-Mediated Mitochondrial Bioenergetics".18. Insights Into Recovery From Acute Fulminant Myocarditis Following Successful Treatment With Ruxolitinib by Comprehensive Single-Cell Profiling.
作者: Juan Qin.;Mandar A Aras.;Evelyn J Song.;Andrew J Connolly.;Lylybell Zhou.;Connor O'Brien.;Joe-Elie Salem.;Arun Padmanabhan.;Javid J Moslehi.
来源: Circulation. 2025年151卷25期1814-1817页 19. Nonculprit Vulnerable Plaques and Prognosis in Myocardial Infarction With Versus Without ST-Segment Elevation: A PROSPECT II Substudy.
作者: Pernille G Thrane.;Michael Maeng.;Akiko Maehara.;Hans Erik Bøtker.;Gary S Mintz.;Lars Kjøller-Hansen.;Thomas Engstrøm.;Mitsuaki Matsumura.;Lak N Kotinkaduwa.;Ole Fröbert.;Jonas Persson.;Rune Wiseth.;Alf I Larsen.;Lisette O Jensen.;Jan E Nordrehaug.;Øyvind Bleie.;Claes Held.;Stefan K James.;Ziad A Ali.;David Erlinge.;Gregg W Stone.
来源: Circulation. 2025年151卷25期1767-1779页
Clinical guidelines recommend different revascularization strategies for nonculprit lesions in patients with ST-segment-elevation myocardial infarction (STEMI) versus non-STEMI (NSTEMI). Whether the prevalence of untreated high-risk vulnerable plaques differs in STEMI and NSTEMI and affects their outcomes is unknown.
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